Predicting recovery of arm movement after a stroke
Prediction of Post-stroke Motor Recovery: the PREP-AVC Algorithm
This study is testing a new method to see if it can accurately predict how well stroke patients will recover their arm movement in the months following their stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT04574037 on ClinicalTrials.gov |
What this trial studies
This observational study aims to validate the PREP2 algorithm, which predicts upper limb motor recovery in stroke patients during the acute phase. By analyzing clinical scores, demographic data, and electrophysiological information, the study will assess the accuracy of recovery predictions at 3-6 months post-stroke. The goal is to enhance patient care by providing insights into expected recovery outcomes, which can inform rehabilitation strategies. Additionally, a new algorithm will be developed to potentially improve prediction accuracy by incorporating cognitive and biological data.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have experienced a stroke resulting in upper limb motor deficits.
Not a fit: Patients with contraindications to MRI or TMS, those under legal guardianship, or without healthcare insurance may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve rehabilitation planning and patient outcomes for stroke survivors.
How similar studies have performed: Previous studies using similar predictive algorithms have shown promising results, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * age ≥ 18 y-o, * admitted in the Pitié-Salpêtrière stroke unit, * stroke with a upper limb motor deficit, * agree to participate; Exclusion criteria: * contra-indication to MRI or TMS, * patients under legal guardianship , * patients without healthcare insurance
Where this trial is running
Paris
- Service des Urgences Cérébro-Vasculaires, Hôpital Pitié Salpêtrière — Paris, France (Recruiting)
Study contacts
- Study coordinator: Charlotte ROSSO, MD
- Email: charlotte.rosso@aphp.fr
- Phone: 1 42 16 21 03
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.