Predicting rebleeding risk in patients with acute gastrointestinal bleeding
Official title: Construction of a Clinical Prediction Model for In-Hospital Rebleeding in Patients With Acute Non-Venous Upper Gastrointestinal Bleeding
Run by Wuhan Central Hospital · NCT06697691 · Data updated 2026-11-12
This study is trying to create a better way to predict which patients who have had serious stomach bleeding are at risk of bleeding again, so doctors can provide better care and prevention.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Wuhan Central Hospital Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | November 22, 2024 |
| Main results expected | December 2024 |
| Study ends | December 2024 |
| Registry record updated | November 27, 2024 |
| Trial ID | NCT06697691 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old diagnosed with acute non-variceal upper gastrointestinal bleeding who have undergone endoscopy within 24 hours of admission.
✕Probably not a fit
Patients with upper gastrointestinal bleeding during hospitalization, variceal bleeding, or those with incomplete clinical data will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a new clinical prediction model for identifying patients at high risk of rebleeding after experiencing acute non-variceal upper gastrointestinal bleeding. Current prediction tools are not sufficiently effective, prompting the need for a more accurate model that incorporates patient symptoms, lab results, and imaging findings. By improving risk assessment, the study seeks to enhance clinical decision-making regarding preventive treatments and monitoring strategies for these patients.
Why it matters
Potential benefit: If successful, this model could significantly reduce the incidence of rebleeding and improve patient outcomes.
How similar studies have gone: While existing prediction tools have been used, this approach aims to create a novel model, indicating it is an untested methodology.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age exceeding 18 years, * Clinical diagnosis of Acute Non-Variceal Upper Gastrointestinal Bleeding , * patients who underwent endoscopy within 24 hours of admission with confirmation of non-variceal bleeding Exclusion Criteria: * Upper Gastrointestinal Bleeding during hospitalization; * transfer from other hospitals; * variceal bleeding; * lower gastrointestinal bleeding.; * bleeding attributed to systemic diseases like disseminated intravascular coagulation (DIC) and hematological disorders; * patients with incomplete clinical data or laboratory test results; * patients who either requested early discharge or declined gastroscopy.
Where it's running
-
the Central Hospital of Wuhan
Wuhan, Hubei, China Recruiting
Study contacts
- Study coordinator: junwei yan
- Email: yanjunweifeng@163.com
- Phone: +8602782211449
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.