Predicting persistent pain after surgery
Personalized Prediction of Persistent Postsurgical Pain
This study is trying to find out what factors might predict if people will have ongoing pain after major surgery by collecting information from patients before and after their operations.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2750 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Washington University School of Medicine Academic / other |
| Locations | 1 site (Saint Louis, Missouri) |
| Trial ID | NCT04864275 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather comprehensive perioperative data from patients undergoing major surgery to identify factors that may predict persistent postsurgical pain. It will collect information on patient history, demographics, physical and cognitive function, psychological markers, and biological indicators related to pain susceptibility. Participants will provide daily assessments of their physical and emotional states, and follow-up evaluations will occur at three and six months post-surgery to analyze pain outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-75 who are scheduled for major surgery and have access to a smartphone.
Not a fit: Patients who do not speak English may not benefit from this study due to language barriers in data collection.
Why it matters
Potential benefit: If successful, this study could lead to better predictions and management strategies for patients at risk of experiencing long-term pain after surgery.
How similar studies have performed: While there have been studies on postoperative pain, this specific approach of using personalized prediction based on a wide range of factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults age 18-75 who are candidates for major surgery (expected surgery duration \>1 hour, and expected overnight admission to the hospital) * Access to a smartphone Exclusion Criteria: * Participants who do not speak English
Where this trial is running
Saint Louis, Missouri
- Washington University in St Louis — Saint Louis, Missouri, United States (Recruiting)
Study contacts
- Principal investigator: Simon Haroutounian, PhD — Associate Professor
- Study coordinator: Karen Frey
- Email: freyk@wustl.edu
- Phone: 314-454-5980
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.