Predicting outcomes for people with cardiovascular-kidney-metabolic syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort will enroll patients with cardiovascular-kidney-metabolic syndrome and collect clinical data, plasma, and whole blood for transcriptomic, proteomic, and metabolomic analysis. Participants will undergo adenosine stress echocardiography to gather detailed cardiac function data and will be followed long term for clinical outcomes. Modern information technology and bioinformatics will be used to link biomarkers and imaging with prognosis and to build a predictive model that combines molecular and clinical information. The goal is to refine risk stratification and guide personalized treatment and follow-up strategies for CKM patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1）Patients who meet the criteria for CKM stages 0-4 were included. 2）Clinical data were complete.

Exclusion Criteria:

* 1\) Presence of infectious diseases during the sample retention period. 2) Presence of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, vasculitis, etc.

  3\) Presence of tumors. 4) Patients with an estimated life expectancy of less than 2 years. 5) Patients with known hypersensitivity to adenosine. 6) Patients who cannot follow up regularly. 7) Pregnant or breastfeeding women, and those participating in other clinical trials.

Where it's running

• Peking University Third Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Shengjia Peng
• Email: 819178014@qq.com
• Phone: 13020535029

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.