Clinical trial Recruiting at 1 site Observational Ages 18 and up

Predicting outcomes for head and neck cancer patients after radiotherapy

Official title: Outcome Prediction in Head&Neck Cancer Patients After Radiotherapy Using Multi-parameter Modelling: Disease Control, Toxicity and Quality of Life

Run by Maastricht Radiation Oncology · NCT01985984 · Data updated 2026-11-12

This study is testing a new follow-up program for head and neck cancer patients to see if it can reduce side effects from radiation while still being effective in treatment.

More Head and Neck Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorMaastricht Radiation Oncology
Academic / other
Drugs / interventionsradiation
Locations1 site (Maastricht)
StatusRecruiting
StartedJuly 2012
Main results expectedJanuary 2030
Study endsJanuary 2030
Registry record updatedOctober 9, 2026
Trial IDNCT01985984 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients planned for curatively intended primary or postoperative radiotherapy for head and neck cancer.

Probably not a fit

Patients who are planned for palliative radiotherapy will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to improve the quality of radiotherapy for head and neck cancer patients by implementing a Standard Follow-up Program (SFP) that reduces radiation-induced side effects while maintaining treatment efficacy. It focuses on developing accurate outcome prediction models that consider various clinical factors, genomic analyses, and treatment-related parameters. By systematically evaluating the effects of new radiation technologies, the study seeks to enhance personalized medicine approaches for patients with head and neck squamous cell carcinoma.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment outcomes and quality of life for head and neck cancer patients undergoing radiotherapy.

How similar studies have gone: Other studies have shown success in using predictive models for cancer treatment outcomes, indicating that this approach has potential for meaningful advancements.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

All patients planned for curatively intended primary or postoperative radiotherapy

Exclusion Criteria:

All patients planned for palliative radiotherapy

Where it's running

  • Maastro Clinic
    Maastricht, Netherlands
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.