Predicting lymphedema risk in breast cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop a nomogram that predicts the risk of lymphedema in breast cancer patients who have undergone axillary lymph node dissection. It focuses on understanding the relationship between arm lymphatic drainage and the occurrence of lymphedema, particularly in patients with residual arm lymph nodes. By identifying high-risk individuals, the study allows for targeted intraoperative interventions to preserve arm lymphatics and potentially prevent lymphedema. The approach combines clinical assessments and surgical techniques to improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 years or older with T1-3 invasive breast cancer;
* Clinically node-positive breast cancer, defined as positive on preoperative axillary palpation, ultrasound examination, and computed tomography scan with contrast;
* Patients who underwent mastectomy with a positive sentinel lymph node (SLN);
* Patients who underwent breast-conserving surgery containing more than two positive SLNs.

Exclusion Criteria:

* Neoadjuvant chemotherapy;
* Previous history of breast cancer.

Where it's running

• Zhongnan Hospital of Wuhan University
  Wuhan, Hubei, China Recruiting

Study contacts

• Principal investigator: Gaosong Wu, Ph.D. — Wuhan University
• Study coordinator: Qianqian Yuan, M.D.
• Email: Yuanqq11@whu.edu.cn
• Phone: 13026322297

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.