Predicting low blood pressure during major upper abdominal surgery
Investigating the Effect of Hypotension Prediction Index Guidance on Intraoperative Hypotension and the Relationships Between the Metabolomic Profile and Postoperative Ileus in Patients Undergoing Major Upper Abdominal Surgery: a Randomized Controlled Trial
This study is testing a new way to predict and manage low blood pressure during major stomach surgeries to help patients avoid complications after their operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 85 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05828862 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of a hypotension prediction index (HPI) to guide management during major upper gastrointestinal surgeries, aiming to reduce the incidence of intraoperative hypotension (IOH). By monitoring patients' blood pressure and utilizing an algorithm to predict impending hypotension, the study seeks to minimize the duration and severity of IOH and its associated postoperative complications. Additionally, it explores the relationship between metabolomic changes and the occurrence of postoperative ileus in patients undergoing these surgical procedures. The outcomes will be assessed both in the short term, within 30 days post-surgery, and long term, within one year.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for elective major upper gastrointestinal surgery who are not undergoing laparoscopic procedures.
Not a fit: Patients undergoing laparoscopic surgery will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative complications and improve recovery times for patients undergoing major upper gastrointestinal surgery.
How similar studies have performed: While the application of HPI in this context is relatively novel, previous studies have shown promise in using predictive algorithms to manage intraoperative hypotension.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * elective upper gastrointestinal surgery Exclusion Criteria: * no laparoscopic surgery
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Chih-Jun Lai, MD
- Email: littlecherrytw@gmail.com
- Phone: 0223123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.