Home › Trials › NCT06814054
Clinical trial Recruiting at 1 site Observational Ages 65 and up

Predicting low blood pressure after anesthesia in older adults using carotid cFT and IVC collapsibility

Official title: Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery

Run by Tanta University · NCT06814054 · Data updated 2026-11-12

We will test whether two ultrasound measurements—carotid corrected flow time (cFT) and the inferior vena cava (IVC) collapsibility index—can predict which older adults having elective surgery will develop low blood pressure after induction of general anesthesia.

Quick facts

Study typeObservational
Ages65 Years and up
SexAll
Enrollment189 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El Gharbyia)
StatusRecruiting
StartedMarch 1, 2025
Main results expectedApril 2026
Study endsMay 2026
Registry record updatedJuly 1, 2025
Trial IDNCT06814054 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Older adults scheduled for elective surgery under general anesthesia who are ASA I–II, have fasted 6–8 hours, and do not have major cardiac, respiratory, or vascular comorbidities.

Probably not a fit

Patients with ASA III–IV, arrhythmias, cardiomyopathy, COPD, BMI > 30 kg/m2, significant peripheral arterial disease, extreme baseline blood pressures, or those who experience difficult intubation or desaturation during induction are unlikely to benefit from these measures in this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study in which clinicians will perform carotid ultrasound to measure corrected flow time and abdominal ultrasound to determine IVC collapsibility before induction of general anesthesia in geriatric patients. Blood pressure will be monitored immediately after induction, and hypotension will be defined by a 30% drop in SBP or 20% drop in MAP from baseline, or an absolute SBP < 90 mmHg or MAP < 65 mmHg within 3 minutes. Patients included are ASA physical status I–II undergoing elective surgery who have fasted 6–8 hours, while those with significant comorbidities (ASA III–IV, arrhythmia, COPD, BMI > 30, peripheral arterial disease) are excluded. The preinduction ultrasound measurements will be compared with the occurrence of postinduction hypotension to determine predictive performance.

Why it matters

Potential benefit: If successful, these noninvasive ultrasound measures could help identify older patients at risk for post-induction hypotension so clinicians can adjust fluid or anesthetic management to reduce organ injury.

How similar studies have gone: Previous work, including reports by Zhang and Critchley, has shown that IVC diameter and collapsibility can predict postinduction hypotension, while carotid corrected flow time has shown some promising but less widely validated results.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* American Society of Anaesthesiologists Physical Status I to Ⅱ
* receiving general anesthesia for elective surgery
* fasted for at least 6 to 8 hours were recruited in this study

Exclusion Criteria:

* • patients who refused to participate in the study

  * American Society of Anaesthesiologists Physical Status Ⅲ or Ⅳ
  * Patients with a history of peripheral arterial diseases or atherosclerosis
  * Patients with body mass index of greater than 30 kg/m2
  * Patients with arrhythmia or cardiomyopathy
  * Chronic obstructive pulmonary disease (COPD)
  * baseline systolic arterial pressure (SAP) ≥ 180 mmHg or \< 90mmHg
  * Any episode of desaturation or difficult intubation during general anasethia induction

Where it's running

  • Faculty of medicine, Tanta university
    Tanta, El Gharbyia, Egypt     Recruiting

Study contacts

  • Principal investigator: tarek Mostafa — tanta university, faculty of medicine
  • Study coordinator: tarek AH Mostafa
  • Email: dr.tarek311@yahoo.com
  • Phone: 01003591332

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
Geriatrics 7Hypotension on Induction 6General Anesthetic Drug Adverse Reaction 4Elective Surgery 5Tanta University 186
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.