Predicting Intra-Abdominal Adhesions Before Surgery
Can the Presence of Intra-Abdominal Adhesion Be Predicted Preoperatively?
Celal Bayar University · NCT06639906
This study is trying to see if certain blood markers can help predict the presence and severity of abdominal adhesions in women who are having surgery after previous abdominal operations.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 54 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Celal Bayar University (other) |
| Locations | 1 site (Manisa) |
| Trial ID | NCT06639906 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the presence of intra-abdominal adhesions using biochemical markers prior to surgery. It will assess the relationship between the severity of adhesions and preoperative blood levels of decorin and TGF β1. The study will involve patients scheduled for laparotomy or laparoscopic surgery for gynecological reasons, specifically those with a history of previous abdominal surgeries. Blood samples will be collected from participants to analyze these markers and their correlation with adhesion severity.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for gynecological abdominal surgery who have had at least one previous cesarean section or abdominal surgery.
Not a fit: Patients who are pregnant, have active infections, or have certain medical conditions such as diabetes or cancer treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve preoperative assessments and surgical outcomes for patients with a history of abdominal surgeries.
How similar studies have performed: While the approach of using biochemical markers for predicting adhesions is promising, it is relatively novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are hospitalized for gynecological reasons with a planned laparotomy or laparoscopic abdominal surgery * Patients with at least 1 previous cesarean section or history of previous abdominal surgery (laparoscopy or laparotomy) Exclusion Criteria: * Patients who do not agree to participate in the study will not be included in the study. * Pregnant patients will not be included in the study (so that the physiological changes of pregnancy do not affect the results) * Presence of preoperative clinical or laboratory findings of infection (such as high fever, tachycardia, leukocytosis, high CRP) * Presence of hematological or coagulation disorders * History or presence of cancer treatment * History or presence of connective tissue disease * Presence of diabetes * Being under 18 years of age will be considered as exclusion criteria.
Where this trial is running
Manisa
- Manisa Celal Bayar University — Manisa, Turkey (RECRUITING)
Study contacts
- Study coordinator: Kemal Sarsmaz, Dr.
- Email: drsarsmazkemal@gmail.com
- Phone: 05068074452
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Adhesions Abdominal, Surgery, Intraabdominal Adhesion, Decorin, TGF β1, Gynecological Abdominal Surgery, Prediction