Predicting inflammatory ureteral polyps in people with ureteral stones
Risk Factors and Development of a Predictive Model for Stone-Associated Inflammatory Ureteral Polyps: A Retrospective Cohort Study With Prospective Validation
This study will try to see if clinical and imaging information can predict inflammatory ureteral polyps in adults having ureteroscopic surgery for ureteral stones.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | The First Hospital of Jilin University Academic / other |
| Locations | 1 site (Changchun, Jilin) |
| Trial ID | NCT07559721 on ClinicalTrials.gov |
What this trial studies
This single-center observational project combines a retrospective cohort (patients treated from 2018–2025) and a currently enrolling prospective validation cohort. Clinical records and preoperative imaging from the retrospective group will be analyzed to identify independent risk factors for inflammatory ureteral polyps. Those factors will be integrated into a preoperative predictive model, which the prospective cohort will be used to validate. The primary outcome is the intraoperative diagnosis of inflammatory ureteral polyps during ureteroscopy.
Who should consider this trial
Good fit: Adults (18 years or older) undergoing ureteroscopic surgery for ureteral calculi at the First Hospital of Jilin University with complete clinical and imaging data and able to provide informed consent.
Not a fit: Patients with bilateral ureteral calculi, preoperative nephrostomy or indwelling ureteral stent, a history of ureteral or bladder cancer, congenital ureteral anomalies, prior ureteral surgery, severe coagulation disorders, or those treated outside the study center are unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If successful, the model could help surgeons identify patients at higher risk of inflammatory ureteral polyps before surgery, improving surgical planning and patient counseling.
How similar studies have performed: Predictive models using clinical and imaging data have been used in other urologic settings, but specific preoperative models for inflammatory ureteral polyps are limited, so this application is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years or older undergoing ureteroscopic surgery for ureteral calculi at the First Hospital of Jilin University. * Complete clinical and imaging data available. Exclusion Criteria: * Patients with bilateral ureteral calculi. * Patients with preoperative nephrostomy or indwelling ureteral stent. * Patients with a history of ureteral or bladder cancer. * Patients with congenital ureteral anomalies or previous ureteral surgery. * Patients with severe coagulation disorders or contraindications to ureteroscopy. * Patients unable to provide informed consent.
Where this trial is running
Changchun, Jilin
- The First Hospital of Jilin University — Changchun, Jilin, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.