Predicting heart events after major non-cardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients aged 45 and older who are at medium-to-high cardiovascular risk and are undergoing major noncardiac surgery. It collects baseline demographic and clinical data, preoperative cardiac biomarkers, and intraoperative information to monitor for myocardial injury and major adverse cardiac events post-surgery. The primary goal is to develop and validate a prediction model for these cardiac events, enhancing preoperative risk assessment and patient management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 45 years;
* Undergoing major noncardiac surgery (expected procedure duration ≥2 h, expected length of postoperative stay ≥2 d);
* History of at least one cardiovascular disease (i.e., coronary artery disease, stroke, congestive heart failure, or peripheral arterial disease) or with at least two cardiovascular risk factors (i.e., hypertension, diabetes, chronic kidney disease, smoking in the past ≥2 years, ≥65 years of age, hypercholesterolemia, history of TIA, high-risk surgery (intrathoracic, intraperitoneal, or major vascular)).

Exclusion Criteria:

* History of acute cardiovascular events within 30 days prior to surgery;
* American Society of Anesthesiologists (ASA) physical status of 5 or greater;
* Previously enrolled in this study;
* Unable to understand or to sign informed consent.

Where it's running

• Nanfang Hospital, Southern Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Bingcheng Zhao, MD
• Email: zhaobch@mail2.sysu.edu.cn
• Phone: 86-13763313653

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.