Predicting glucose metabolism issues after pregnancy in women with gestational diabetes
Early Prediction of Postpartum Glucose Metabolism Abnormalities in Gestational Diabetes Mellitus Based on Gestational Metabolic Profile and Lipid Profile
Women's Hospital School Of Medicine Zhejiang University · NCT05670548
This study is trying to find ways to predict glucose metabolism problems after pregnancy in women who had gestational diabetes, so they can get help sooner.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 20 Years to 49 Years |
| Sex | Female |
| Sponsor | Women's Hospital School Of Medicine Zhejiang University (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT05670548 on ClinicalTrials.gov |
What this trial studies
This project aims to identify reliable serum markers in pregnant women diagnosed with gestational diabetes mellitus (GDM) using advanced metabolic and lipid profiling techniques. By employing high-throughput mass spectrometry, the study seeks to develop a predictive model for postpartum glucose metabolism abnormalities. Additionally, a management system based on this model will be created to enhance early detection and intervention strategies for women at risk of abnormal glucose metabolism after childbirth.
Who should consider this trial
Good fit: Ideal candidates are pregnant women diagnosed with gestational diabetes mellitus between 24-28 weeks of gestation, planning to give birth at the research center.
Not a fit: Patients with pre-existing metabolic disorders or other serious health conditions that could affect pregnancy outcomes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to early identification and management of glucose metabolism issues in postpartum women, improving long-term health outcomes.
How similar studies have performed: While similar predictive models have been explored, this specific approach utilizing high-throughput mass spectrometry for early prediction in GDM is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Plan to have routine prenatal examinations and give birth in the research center * GDM was diagnosed at 24-28 gestational weeks * Singleton pregnancy * Without other pregnancy complications * Willing to cooperate with the hospital to follow up Exclusion Criteria: * Have diseases that affect metabolic function or even threaten the life of the mother and fetus before pregnancy, such as diabetes, heart disease, liver and kidney diseases, thyroid diseases with drug, autoimmune diseases, malignant tumors, AIDS, etc. * Fetus has a known deformity or genetic defects * Incomplete clinical data
Where this trial is running
Hangzhou, Zhejiang
- Women's Hospital School Of Medicine Zhejiang University — Hangzhou, Zhejiang, China (RECRUITING)
Study contacts
- Study coordinator: Zhaoxia Liang, Prof.
- Email: xiaozaizai@zju.edu.cn
- Phone: 86571-89992115
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gestational Diabetes Mellitus