Predicting gestational diabetes in early pregnancy using continuous glucose monitoring.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to predict gestational diabetes mellitus (GDM) in pregnant women during the first trimester by utilizing continuous glucose monitoring. GDM is a common complication of pregnancy that can lead to various maternal and neonatal health issues. The study will involve monitoring glucose levels in women who meet specific eligibility criteria, including being at least 18 years old and having a singleton pregnancy. The goal is to identify women at risk for GDM earlier than the traditional screening methods, which typically occur later in pregnancy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Maternal age ≥ 18 years
* Planned antenatal care at the same centre (i.e. not planning to move before delivery).
* Singleton pregnancy.
* Informed and written consent.

Exclusion Criteria:

* Age \<18 years;
* Multiple pregnancy in current pregnancy;

  * Unconscious or very ill; · Serious mental illness;
  * Learning difficulties;
  * Not fluent in local language and absence of interpreter;
  * Severe congenital anomaly on ultrasound;
  * Pre-existing diabetes mellitus type 1 or 2;
  * Patients undergoing metformin therapy for infertility.
  * Significant pre-pregnancy comorbidities that increase risk in pregnancy, for example renal failure, severe liver disease, transplantation, cardiac failure, psychiatric conditions requiring in-patient admission (\<1 year);
  * Significant co-morbidity in the current pregnancy, nephropathy (estimated GFR \<60ml/min), other physical or psychological conditions likely to interfere with the conduct of the study and/or interpretation of the trial results;
  * Participating in another intervention study that influences outcomes of this study;
  * Allergy to adhesive materials;
  * Allergy to any of the components of the glucose test:

Where it's running

• Hcuva
  El Palmar, Murcia, Spain Recruiting

Study contacts

• Principal investigator: Catalina de Paco Matallana, MD — Hcuva
• Study coordinator: Catalina de Paco Matallana, MD
• Email: katy.depaco@gmail.com
• Phone: 968369500

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Prenatal Exercise to See How Cardio or Strength Training Affects Blood Sugar

  This study tests whether different types and amounts of exercise during pregnancy can improve blood sugar control in women with gestational diabetes.

  Recruiting University of Central Arkansas · Conway, Arkansas · NCT07802262

• Maternal insulin and fat metabolism in pregnancies at risk for preeclampsia and gestational diabetes

  This project will try to see if insulin resistance and how the body burns fats early in pregnancy predict later preeclampsia or gestational diabetes in people at higher risk.

  Recruiting University of Tennessee Graduate School of Medicine · Knoxville, Tennessee · NCT07565727

• Behavioral toolkit to help pregnant women manage gestational diabetes and pregnancy-related high blood pressure.

  This program will test whether a structured behavioral toolkit helps pregnant women with both gestational diabetes and pregnancy-induced high blood pressure better control their blood sugar and blood pressure.

  Recruiting at 2 sites University of the Punjab · Lahore, Punjab Province and 1 other locations · NCT07551011

• Early pregnancy lifestyle patterns and glucose changes in a TOFFFY sub-study

  This study tests whether daily patterns like sleep, activity, and meal timing in early pregnancy affect glucose levels and the risk of gestational diabetes, using CGM and wearable data in pregnant women in Singapore.

  Recruiting KK Women's and Children's Hospital · Singapore, Singapore · NCT07534670

• Using a 24-hour continuous glucose monitor after delivery to predict future Type 2 diabetes risk in people with gestational diabetes

  This pilot tests whether wearing a continuous glucose monitor for 24 hours immediately after delivery can help predict later Type 2 diabetes risk in people who had gestational diabetes.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07449039

• Continuous glucose monitoring to find and manage early high blood sugar in pregnancy

  This uses continuous glucose monitors in early pregnancy for people without diabetes to find and treat high blood sugar and try to reduce problems for mother and baby.

  Recruiting at 8 sites Jaeb Center for Health Research · Birmingham, Alabama and 9 other locations · NCT06957028

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.