Predicting early relapse in lung cancer patients after surgery
Official title: Utilizing Perioperative Variation Trends of Circulating Tumor Cells and Tumor Pathological Characteristics as a Combined Relapse Prediction Model for Resectable Non-Small Cell Patients - a Prospective Clinical Feasibility Trial
Run by Chang Gung Memorial Hospital · NCT06262386 · Data updated 2026-11-12
This study is testing a new way to predict early relapse in lung cancer patients after surgery by looking at changes in their tumor cells and seeing if giving them chemotherapy helps improve their outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 90 Years |
| Sex | All |
| Enrollment | 358 (estimated) |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Taoyuan City) |
| Status | Recruiting |
| Started | August 1, 2023 |
| Main results expected | July 31, 2028 |
| Study ends | July 31, 2028 |
| Registry record updated | February 16, 2024 |
| Trial ID | NCT06262386 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with resectable non-small cell lung cancer who have undergone tumor resection and are at clinical stage 1a to 3a.
✕Probably not a fit
Patients with pathologic stage greater than 3b or those who cannot complete treatment or provide blood samples for CTC analysis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to develop a combined relapse prediction model for patients with resectable non-small cell lung cancer who have undergone tumor resection. The study focuses on identifying patients at risk of early relapse by analyzing circulating tumor cells (CTCs) and their behavior post-surgery. By monitoring changes in CTC levels within the first three days after surgery, the trial seeks to improve early detection of potential relapses, which could lead to better patient management and outcomes. The intervention involves administering cisplatin-based chemotherapy to eligible participants.
Why it matters
Potential benefit: If successful, this study could provide a reliable method for early detection of relapse in lung cancer patients, potentially improving survival rates.
How similar studies have gone: While studies have explored the role of circulating tumor cells in cancer relapse, this specific approach to predicting early relapse in resectable lung cancer is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients who presented with resectable disease ( Clinical stage 1a to 3a) 2. Patients who received tumor resection Exclusion Criteria: 1. Pathologic stage greater than stage 3b or 4 2. Pathologic stage less than stage 1a1 3. Could not complete treatment course 4. Could not receive blood sampling for CTC (circulating tumor cell) or regular surveillance
Where it's running
-
Ching-Yang Wu
Taoyuan City, Taiwan Recruiting
Study contacts
- Principal investigator: Ching-Yang Wu — Chang Gung Memorial Hospital
- Study coordinator: Ching-Yang Wu
- Email: wu.chingyang@gmail.com
- Phone: +886975368204
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.