Predicting chronic pain after breast surgery

Development of Predictive Models Using Artificial Intelligence for Postoperative Chronic Pain and Opioid Use Following Breast Surgery: A Prospectively-Designed Study

Observational University of California, San Diego · NCT04967352

This study is trying to see if using artificial intelligence can help predict which patients might experience long-term pain and need more pain medication after major breast surgery.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, San Diego Academic / other
Locations1 site (La Jolla, California)
Trial IDNCT04967352 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop predictive models using artificial intelligence to assess the risk of acute and chronic pain, as well as opioid use, in patients undergoing major breast surgery. Data will be collected prospectively from participants, including surveys on pain and psychological factors, pharmacogenomic information, preoperative comorbidities, and demographic details. The study seeks to personalize pain management strategies by identifying patients at higher risk for chronic pain and opioid dependence following surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled to undergo major breast surgery, such as mastectomy or breast reconstruction.

Not a fit: Patients who are undergoing simple lumpectomy or those who refuse to consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to tailored pain management strategies that reduce the incidence of chronic pain and opioid dependence in breast surgery patients.

How similar studies have performed: Other studies have shown promise in using predictive models for pain management, but this specific approach focusing on breast surgery is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient undergoing major breast surgery (except for simple lumpectomy)

Exclusion Criteria:

* refusal to consent
* lack of independent decision-making capacity
* inability to communicate effectively with research personnel

Where this trial is running

La Jolla, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainOpioid UseBreast PainBreast Cancer
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.