Predicting anxiety disorders in men with premature ejaculation

Development and Validation of an Anxiety Disorder Prediction Model for Premature Ejaculation Patients

Observational Xijing Hospital · NCT06677814

This study is trying to see if men with premature ejaculation are more likely to develop anxiety disorders, so doctors can help them earlier.

Quick facts

Study typeObservational
Enrollment700 (estimated)
Ages18 Years and up
SexMale
SponsorXijing Hospital Academic / other
Locations2 sites (Xi'an, Shaanxi and 1 other locations)
Trial IDNCT06677814 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop and validate a predictive model for identifying male patients with premature ejaculation (PE) who are at high risk of developing anxiety disorders. By enrolling participants from multiple clinical centers, the study will utilize comprehensive assessments, including validated questionnaires and clinical interviews, to gather baseline data. The goal is to facilitate early intervention strategies that can improve patient outcomes and address the psychological impacts of PE.

Who should consider this trial

Good fit: Ideal candidates are heterosexual men diagnosed with premature ejaculation who are in stable monogamous relationships.

Not a fit: Patients who are minors, have a sexual orientation other than heterosexual, or have recently taken anti-anxiety medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this model could lead to earlier identification and treatment of anxiety disorders in men with premature ejaculation, enhancing their quality of life.

How similar studies have performed: While the approach of developing predictive models for anxiety in sexual dysfunction is not widely tested, similar studies have shown promise in related fields.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Comply with the international medical premature ejaculation diagnostic criteria
* Individuals with a "heterosexual" orientation who engage in vaginal intercourse
* Having a stable relationship with "monogamy"
* The International Index of Erectile Function-5 scale is ≥17 points, indicating that the patient has no erectile dysfunction or only mild erectile dysfunction
* Be informed of the purpose of this study, support this study, and complete the informed consent form

Exclusion Criteria:

* Minors under the age of 18
* Individuals with a sexual orientation of "gay" or "bisexual"
* The judgment of "ejaculation too fast" is based only on masturbation or non-vaginal sexual intercourse
* The score of the premature ejaculation self-assessment scale is ≤8 points
* Suffering from diseases that may affect anxiety symptoms (hyperthyroidism/hypothyroidism, digestive diseases, malignant tumors, etc.)
* Within 2 months, have taken anti-anxiety drugs and/or drugs for PE treatment
* Those with a history of severe neurological diseases (such as epilepsy) and/or a history of schizophrenia, bipolar disorder, or other mental disorders
* Poor cooperation during diagnostic interviews

Where this trial is running

Xi'an, Shaanxi and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Premature EjaculationAnxiety
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.