Clinical trial Recruiting at 1 site Observational Ages 18 and up

Predicting adverse outcomes in patients with acute pulmonary embolism using CT scans

Official title: A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using Parameters Obtained by Computed Tomographic Pulmonary Angiography.

Run by Shengjing Hospital · NCT05098769 · Data updated 2026-11-12

This study is trying to see if using CT scans and other information can help doctors predict serious problems in patients with acute pulmonary embolism within 30 days of being admitted to the hospital.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorShengjing Hospital
Academic / other
Locations1 site (Shenyang, Liaoning)
StatusRecruiting
StartedJanuary 18, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMarch 11, 2026
Trial IDNCT05098769 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 years and older diagnosed with acute pulmonary embolism based on CT pulmonary angiography.

Probably not a fit

Patients who are pregnant, have received reperfusion treatment before admission, or have incomplete data regarding key clinical parameters will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects clinical, laboratory, and CT parameters from patients diagnosed with acute pulmonary embolism upon hospital admission. The aim is to predict adverse outcomes within 30 days post-admission by developing a multivariable logistic regression model. Patients are divided into derivation and validation cohorts to evaluate the model's effectiveness against established risk stratification systems. The study focuses on enhancing predictive capabilities for better patient management.

Why it matters

Potential benefit: If successful, this study could improve the ability to predict adverse outcomes in acute pulmonary embolism patients, leading to better clinical decision-making and patient care.

How similar studies have gone: While predictive modeling in acute pulmonary embolism is an established area, the specific approach of this study may offer novel insights and improvements over existing risk stratification methods.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age of ≥ 18 years and a PE diagnosis based on CT pulmonary angiography

Exclusion Criteria:

* pregnancy
* reception of reperfusion treatment before admission
* missing data regarding CT parameters, echocardiography, cardiac troponin I (c-Tn I), and N-terminal-pro brain natriuretic peptide (NT-pro BNP) levels.

Where it's running

  • Shenjing Hospital of CHINA MEDICAL UNIVERSITY
    Shenyang, Liaoning, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.