Pre-surgery focused radiation for spinal metastases.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients with spinal metastases receive hypofractionated stereotactic body radiotherapy (SBRT) to the involved spinal segments shortly before surgical decompression and/or stabilization. Imaging with MRI and CT is performed before surgery and at 3 and 6 months after surgery to measure local tumor control. Participants also complete standardized pain, functional status, and quality-of-life questionnaires to track postoperative outcomes. Safety, perioperative complications, and changes in pain and function are recorded as secondary measures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Indication for surgical treatment of a spinal tumor
* Age: older or 18 years
* Estimated survival \> 6 months
* The patient is able to understand the nature, significance and scope of the clinical study in the context of patient information and to base the decision to participate in the study on this.

Exclusion Criteria:

* Age: \< 18 years
* Motor deficit or loss of bladder and bowel control that urges an emergency surgical decompression
* Tumor extent does not allow hypofractioned SBRT (1-3 fractions)

Where it's running

• University Medical Center Goettingen
  Göttingen, Germany Recruiting

Study contacts

• Study coordinator: Carla Marie Zwerenz, Dr. med.
• Email: carlamarie.zwerenz@med.uni-goettingen.de
• Phone: +49 551 39 64501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.