Pre-operative exercise and education for knee replacement patients

Effect of Prehabilitation Before Total Knee Replacement on Post-operative Patient-reported Joint Awareness, Enablement and Knee Function

NA · Linkoeping University · NCT06290336

This study is testing if a special exercise program and education before knee replacement surgery can help patients feel better and recover faster compared to just getting standard information.

Quick facts

PhaseNA
Study typeInterventional
Enrollment110 (estimated)
Ages40 Years to 85 Years
SexAll
SponsorLinkoeping University (other gov)
Locations1 site (Linköping, Östergötland County)
Trial IDNCT06290336 on ClinicalTrials.gov

What this trial studies

This multi-center randomized controlled trial aims to evaluate the effects of pre-operative exercise therapy and education on patients awaiting knee replacement surgery. Participants will be randomly assigned to either an intervention group, receiving supervised exercise and education, or a control group, receiving standard pre-operative information. The study will assess subjective knee function, patient satisfaction, and enablement at various intervals post-surgery. The intervention includes individualized strength, balance, and mobility exercises, along with discussions about recovery expectations and rehabilitation.

Who should consider this trial

Good fit: Ideal candidates are individuals awaiting primary unilateral knee replacement surgery due to knee osteoarthritis and residing within 60 minutes of the intervention site.

Not a fit: Patients who have had previous knee replacement surgery or have other primary reasons for surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved knee function and higher patient satisfaction after knee replacement surgery.

How similar studies have performed: Other studies have shown positive outcomes with pre-operative exercise and education, suggesting this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Waiting list for primary unilateral knee replacement surgery
* Osteoarthritis of the knee being the primary reason for surgery
* Reside within 60 minutes of travel to the site of the intervention

Exclusion Criteria:

* Previous knee replacement surgery in the other knee
* Other reason than osteoarthritis of the knee as the primary reason for surgery
* Impaired cognitive function
* Not being independent speaking and reading in swedish language
* Chronic illness or disability etc hindering full participation in the intervention

Where this trial is running

Linköping, Östergötland County

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Knee Osteoarthritis, Knee replacement, Exercise therapy, Education, Knee function, Satisfaction

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.