Postoperative pain and short-term success after two root canal filling methods: cold lateral condensation versus warm vertical obturation
Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques - A Randomized Controlled Trial
This trial will test whether warm vertical obturation or cold lateral condensation causes less postoperative pain and better short-term healing in adults having root canal treatment for single-rooted necrotic teeth with asymptomatic apical periodontitis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Jordan Academic / other |
| Locations | 1 site (Amman, Amman Governate) |
| Trial ID | NCT07310212 on ClinicalTrials.gov |
What this trial studies
This is a randomized, parallel-group clinical trial comparing postoperative pain and short-term clinical and radiographic outcomes after two obturation techniques in single-rooted necrotic teeth. All treatments are performed by one experienced operator using standardized rotary instrumentation, irrigation, working length determination, and isolation to isolate the effect of obturation technique. Participants are randomly assigned to either cold lateral condensation with an epoxy resin sealer or warm vertical thermoplasticized gutta-percha (Obtura II). Postoperative pain will be recorded in the early healing period alongside patient-reported outcomes and short-term radiographic healing.
Who should consider this trial
Good fit: Adults (18+) with single-rooted necrotic teeth diagnosed radiographically and clinically with asymptomatic apical periodontitis who can provide informed consent are ideal candidates.
Not a fit: Patients with symptomatic apical periodontitis, previously treated root canals, multi-rooted teeth, significant periodontal disease, pregnancy/lactation, or systemic conditions or medications that alter pain perception are unlikely to benefit from the findings.
Why it matters
Potential benefit: If successful, the results could help clinicians choose an obturation method that reduces early postoperative pain and improves short-term healing after root canal treatment.
How similar studies have performed: Laboratory work and some small clinical studies suggest warm vertical techniques may improve gutta-percha adaptation, but direct clinical comparisons of postoperative pain are limited and results are mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older. * Patients requiring endodontic treatment for single-rooted necrotic teeth. * Radiographic and clinical diagnosis of asymptomatic apical periodontitis. * Ability to understand the study and provide written informed consent. Exclusion Criteria: * Teeth diagnosed with symptomatic apical periodontitis. * Pregnant or lactating women. * Patients with systemic diseases affecting pain perception (e.g., uncontrolled diabetes, chronic pain conditions). * Teeth that have been previously endodontically treated. * Patients taking medications that may influence pain perception (e.g., chronic analgesic or anti-inflammatory drug use). * Periodontally compromised teeth with significant bone loss or mobility.
Where this trial is running
Amman, Amman Governate
- University of Jordan Hospital — Amman, Amman Governate, Jordan (Recruiting)
Study contacts
- Study coordinator: Dalin Jihad AlSawaftah, Endodontic resident, DDs
- Email: dalin7495@gmail.com
- Phone: +962779420787
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.