Clinical trial Recruiting at 2 sites Interventional Ages 40 to 70

Post-market skin care for after full-face laser treatment with Ariessence Pure PDGF+

Official title: A Multi-center, Post-market Cosmetic Evaluation of Ariessence™ Pure PDGF+ Following Ablative Laser for the Tolerability and Improvement in the Appearance of Aging Skin.

Run by Lynch Regenerative Medicine · NCT07718347 · Data updated 2026-11-12

This post-market study tests whether applying Ariessence Pure PDGF+ after an ablative laser helps people feel more comfortable and improves skin appearance compared to a standard emollient.

More Aging trials

Quick facts

Study typeInterventional
Ages40 Years to 70 Years
SexAll
Enrollment21 (estimated)
SponsorLynch Regenerative Medicine
Research network
Locations2 sites (Sacramento, California and 1 other locations)
StatusRecruiting
StartedApril 16, 2026
Main results expectedNovember 2026
Study endsFebruary 2027
Registry record updatedJuly 21, 2026
Trial IDNCT07718347 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 40-65 with Glogau III-IV aging skin, Fitzpatrick II-IV, suitable for ablative laser, non-smokers for at least 3 years, and willing to follow post-procedure care with documentation.

Probably not a fit

Patients outside the age range, with Fitzpatrick I or > IV, active skin disease, recent facial procedures, or pregnancy/lactation may receive no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multi-center, post-market cosmetic evaluation evaluating Ariessence Pure PDGF+ as a leave-on solution applied to the full face after ablative laser treatment. The study compares tolerability and cosmetic outcomes between Ariessence and Aquaphor using subject diaries, investigator assessments, and standardized photos on days 3, 7, and 14. Participants are adults ages 40-65 with mid-to-severe aging concerns (Glogau III-IV) and Fitzpatrick II-IV, who are non-smokers and suitable for ablative laser. Excluded are those with active skin disease, recent facial procedures, pregnancy, implants, or history of keloids. Lead sponsor is Lynch Regenerative Medicine and participating sites are in California and Tennessee.

Why it matters

Potential benefit: If successful, Ariessence could reduce post-procedure discomfort and improve early skin appearance after laser treatment.

How similar studies have gone: Post-procedure topical growth factor products have shown potential benefits in some cosmetic procedures, but this exact post-market evaluation is relatively novel in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria

-:Adults 40-65 70 years

* Glogau III-IV
* Fitzpatrick II-IV.
* Suitable for ablative laser
* non-smoker ≥ 3 years
* Willing to comply with post-procedure regimen
* patient reported outcome documentation, and photo documentation.

Exclusion Criteria:

* Fitzpatrick I or \> IV,
* recent facial procedures (\< 6 months)
* active skin disease
* pregnancy/lactation
* implanted devices
* history of keloids.

Where it's running

  • Laser & Skin Surgery Medical Group
    Sacramento, California, United States
    Recruiting
  • The Practice of Brian S. Biesman, MD
    Nashville, Tennessee, United States
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.