Post-ICU care program for improving recovery

Evaluation of Structured, Multidisciplinary and Personalized Post-ICU Care on Physical and Psychological Functioning, and Quality of Life of Former ICU Patients

NA · Radboud University Medical Center · NCT05066984

This study is testing a new personalized care program for people recovering from critical illness in the ICU to see if it helps them feel better and improves their quality of life compared to standard care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment2250 (estimated)
Ages18 Years and up
SexAll
SponsorRadboud University Medical Center (other)
Locations2 sites (Nijmegen, Gelderland and 1 other locations)
Trial IDNCT05066984 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness and cost-effectiveness of a structured, multidisciplinary, and personalized post-ICU care program compared to usual care for patients recovering from critical illness. The intervention is designed to address both physical and psychological functioning, as well as overall quality of life for ICU survivors. The study will follow participants for one to two years post-ICU to assess outcomes such as quality of life and cognitive functioning. It involves a stepped wedge cluster randomized controlled trial across five hospitals.

Who should consider this trial

Good fit: Ideal candidates are adult ICU patients at high risk of post-ICU syndrome who are 18 years or older and can understand Dutch.

Not a fit: Patients discharged directly to nursing homes, rehabilitation clinics, or for palliative care may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance the recovery and quality of life for ICU survivors.

How similar studies have performed: Other studies have shown promising results with structured post-ICU care approaches, indicating potential for success in this novel intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ICU patients at high risk of critical illness-associated morbidity post-ICU
* 18 years or older
* Patient or legal representative understands the Dutch language

Exclusion Criteria:

* Patients discharged from ICU/hospital direct to a nursing home
* Patients discharged from ICU/hospital direct to a medical or geriatric rehabilitation clinic
* Patients discharged for palliative care

Where this trial is running

Nijmegen, Gelderland and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post ICU Syndrome, post-ICU care, cost-effectiveness, QoL, PROMs

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.