Post-filter hematocrit calculation for adults on continuous renal replacement therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Filter clotting is a common complication of continuous renal replacement therapy (CRRT) that leads to blood loss, reduced treatment efficacy, and higher cost. This single-center validation compares a calculated post-filter hematocrit using the proposed formula HCTpost = HCTpre/(FF(HCTpre-1)+1) with directly measured post-filter hematocrit values from CRRT machines. Adult patients receiving CRRT (age ≥18) will be sampled, with patients on ECMO excluded, and paired calculated and measured values will be analyzed to determine agreement. The study is a cross-sectional diagnostic/method-comparison effort to determine whether the formula provides sufficiently accurate estimates for clinical use.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients initiated on CRRT age equal than or greater to 18 years of age

Exclusion Criteria:

* patients on ECMO

Where it's running

• University of Iowa Hospitals and Clinics
  Iowa City, Iowa, United States Recruiting

Study contacts

• Study coordinator: Gwyndolyn M Radford, MD
• Email: gradford@uiowa.edu
• Phone: 7858179620

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Intra-Abdominal Pressure Changes During CRRT in Critically Ill Adults

  This study tests how intra-abdominal pressure changes in critically ill adults on continuous renal replacement therapy using a bladder pressure measurement.

  Recruiting Bursa Yuksek Ihtisas Training and Research Hospital · Bursa, Bursa · NCT07823387

• Preventing kidney injury after heart surgery

  This study is testing if Coenzyme Q10 and Glutathione can help prevent kidney injury in patients having heart surgery.

  Recruiting Phase 2 George Washington University · Washington D.C., District of Columbia · NCT06620523

• Pediatric use of multiFiltratePRO for CVVHD in kids

  This study tests whether the paediatric mode of multiFiltratePRO can deliver at least 80% of the prescribed CVVHD dose within 72 hours in children with acute kidney injury.

  Recruiting at 2 sites Fresenius Medical Care Deutschland GmbH · Ostrava-Poruba and 1 other locations · NCT06603324

• Comparing two dialysis techniques for kidney injury in ICU patients

  This study is testing whether a new dialysis method using citrate is just as good as a traditional method using heparin for helping ICU patients with kidney injury lower their urea levels.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06369064

• Hand ischaemia risk after creating an arteriovenous fistula

  This study will see how often and why adults with stage 5 chronic kidney disease develop short- or medium-term hand ischaemia after an arteriovenous fistula is created.

  Recruiting GCS Ramsay Santé pour l'Enseignement et la Recherche · Paris · NCT06297343

• Induction treatment for newly diagnosed multiple myeloma patients with renal failure

  This study is testing a new treatment plan for people with newly diagnosed multiple myeloma and kidney problems to see if it helps them respond better to therapy.

  Recruiting Early Phase 1 Augusta University · Augusta, Georgia · NCT06142396

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.