Positioning the saccule and utricle in CT scans for otosclerosis
KNOW HOW TO POSITION THE SACCULE AND UTRICULE IN SCANNING: INTEREST IN INTRAVESTIBULAR DISLOCATIONS OF PISTONS OR CALIPER
University Hospital, Strasbourg, France · NCT06179251
This study is testing a new way to use CT scans to better see and understand the inner ear structures in people with otosclerosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France (other) |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT06179251 on ClinicalTrials.gov |
What this trial studies
This study aims to improve the interpretation of vestibular structures in patients with otosclerosis by analyzing six reference sections from histology, high-resolution T2 MRI, and CT scans. The researchers will compare these sections with precise topographical landmarks to accurately position the posterior membranous labyrinth in CT imaging. This approach seeks to overcome the limitations of MRI artifacts caused by titanium pistons, which hinder the assessment of the vestibule. By utilizing CT, which has fewer contraindications and is more widely available, the study hopes to enhance diagnostic capabilities for otosclerosis.
Who should consider this trial
Good fit: Ideal candidates include adults and minors who have undergone MRI or CT scans of the internal ear canals and have normal imaging results on the side opposite the pathology.
Not a fit: Patients who have expressed opposition to participating in the study or have imaging artifacts will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy for patients with otosclerosis, facilitating better treatment planning.
How similar studies have performed: While this approach is innovative, it builds on existing imaging techniques; however, its specific application to otosclerosis has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years old) and minors (≥ 6 years old) * Subject having received an MRI of the internal ear canals from the HUS between 01/01/2018 and 01/01/2021 or a CT scan of the rocks between 07/01/2015 and 01/01/2021 * Normal MRI or CT on the side opposite the pathology. * Normal tonal audiogram on the side opposite the pathology (peripheral facial paralysis assumed to be cold for MRI and petrous fracture for CT). * Subject who has not expressed his opposition, after information, to the reuse of his data for the purposes of this research. * Holders of authority who have not expressed their opposition, after information, to the reuse of their child's data for the purposes of this research Exclusion Criteria: * Subject having expressed opposition to participating in the study * Holders of parental authority who have expressed their opposition to the reuse of their child's data for the purposes of this research * Imaging with artifacts * Absence of pure-tone audiogram or its abnormality on the side of the ear studied * Any malformation or pathology of the vestibule on imaging on the side of the ear studied * Subjects under guardianship or curatorship
Where this trial is running
Strasbourg
- Service de Radiologie - CHU de Strasbourg - France — Strasbourg, France (RECRUITING)
Study contacts
- Study coordinator: francis VEILLON, MD, PhD
- Email: francis.veillon@chru-strasbourg.fr
- Phone: 33 3 88 12 78 65
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Otosclerosis, Vestibular dysfunction, Membranous Labyrinth