Polypropylene versus polyglactin for subcuticular closure of upper limb wounds
Polypropylene Versus Polyglactin in Upper Limb Subcuticular Skin Closure: Results From a Randomized Controlled Trial.
This trial will test whether polypropylene or polyglactin sutures give better cosmetic scars when used to close upper limb surgical wounds in adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Shebin El-Kom Teaching Hospital Academic / other |
| Locations | 1 site (Menoufia Governorate) |
| Trial ID | NCT07582679 on ClinicalTrials.gov |
What this trial studies
This interventional comparison enrolls adults undergoing upper limb procedures and assigns subcuticular skin closure with either non-absorbable polypropylene or absorbable polyglactin sutures. The primary outcome is cosmetic appearance of the scar, while secondary outcomes include wound complications, patient-reported discomfort and satisfaction, and the effect of elective versus trauma surgery. Eligible participants are adults (≥18) with wounds suitable for primary subcuticular closure treated at Shebin El Koum Teaching Hospital. Patients with heavily contaminated wounds, uncontrolled diabetes, significant tissue loss, immunosuppression, or known allergy to suture material are excluded.
Who should consider this trial
Good fit: Adults aged 18 or older undergoing upper limb surgery with wounds suitable for primary subcuticular closure who can provide informed consent are the ideal candidates.
Not a fit: Patients with heavily contaminated or infected wounds, uncontrolled diabetes, chronic steroid use or other immunosuppression, crush injuries or significant tissue loss, delayed primary closure, or known allergy to the suture materials are unlikely to benefit from this comparison.
Why it matters
Potential benefit: If successful, the findings could help surgeons choose the suture that produces better-looking scars and fewer wound problems for upper limb closures.
How similar studies have performed: Previous comparisons of absorbable versus non-absorbable sutures have reported mixed or inconclusive results and generally did not use standardized scar outcomes specifically for upper limb subcuticular closure.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged ≥18 years * Patients undergoing any surgical procedure involving the upper limb * Procedures performed in either elective or emergency settings * Wounds suitable for primary subcuticular skin closure * Ability to provide informed consent Exclusion Criteria: * Heavily contaminated or infected wounds * Patients with uncontrolled diabetes mellitus, chronic steroid use, immunosuppression or peripheral vascular disease * Crush injuries and wounds with significant tissue loss * Known allergy to suture material * Delayed primary closure wounds
Where this trial is running
Menoufia Governorate
- Shebin El Koum teaching Hospital — Menoufia Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed Elsaid Hamisa
- Email: mohamedhamisa442@gmail.com
- Phone: +201092248136
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.