Point-of-care blood test to detect brain injury in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling children 0–17 years old who present with non-penetrating head trauma and have blood drawn as part of emergency care. Blood samples collected within 24 hours of injury are analyzed at the bedside using the i-STAT TBI cartridge for GFAP and UCH-L1 concentrations. Results will be compared to head CT or MRI findings in the TBI group to see how well the biomarkers predict intracranial injury. Clinical outcomes for surviving TBI patients will be collected by telephone interview with a parent at 3 and 6 months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 0-17 years of age
* Presentation of non-penetrating trauma
* Blood draw within 24 hours of injury
* For TBI group: head CT or MRI obtained

Exclusion Criteria:

* Presentation to Children's Nebraska after 24 hours of injury
* 18 years of age or older

Where it's running

• Children's Nebraska
  Omaha, Nebraska, United States Recruiting

Study contacts

• Principal investigator: Grace Lai, MD, PhD — University of Nebraska
• Study coordinator: Megan McChesney, BSN, RN, CPN
• Email: mmcchesney@unmc.edu
• Phone: 531-375-3835

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.