Clinical trial Recruiting at 1 site Interventional Ages 6 to 12

Play-based nerve mobilization to improve hand strength and dexterity in children with diplegic cerebral palsy

Official title: Effects of Play Based Neural Mobilisation Activities on Hand Grip Strength and Dexterity in Cerebral Palsy Children

Run by Riphah International University · NCT07428928 · Data updated 2026-11-12

This trial will try adding play-based nerve mobilization to regular physical therapy to see if it improves hand grip strength and dexterity in children aged 6–12 with diplegic cerebral palsy.

More Cerebral Palsy trials

Quick facts

Study typeInterventional
Ages6 Years to 12 Years
SexAll
Enrollment34 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedOctober 29, 2025
Main results expectedFebruary 20, 2026
Study endsFebruary 20, 2026
Registry record updatedFebruary 24, 2026
Trial IDNCT07428928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children aged 6–12 with diplegic cerebral palsy who are GMFCS level III–IV and MACS II–III, can follow commands, and have no major injuries in the past year.

Probably not a fit

Children who cannot follow commands, have a recent upper-limb injury, associated scoliosis, or non-diplegic forms of cerebral palsy are unlikely to benefit from this specific program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, single-blind controlled trial will enroll 16 children (age 6–12) with diplegic cerebral palsy (GMFCS III–IV, MACS II–III) at clinics in Lahore and randomly assign them to routine physical therapy with or without play-based neural mobilization. The intervention uses game-like activities (for example, a Simon Says format) to mobilize the ulnar, median, and radial nerves alongside standard therapy. Primary outcomes are hand grip strength measured with a dynamometer and manual dexterity measured with a pegboard test, collected over a 10-month study period. Convenience sampling is used and data will be analyzed in SPSS.

Why it matters

Potential benefit: If successful, this low-cost, play-based addition could improve hand strength and dexterity and help children with daily self-care and play.

How similar studies have gone: Neural mobilization has shown functional and pain benefits in some musculoskeletal and neuropathic adult studies, but play-based nerve mobilization specifically in children with cerebral palsy is novel and evidence is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion Criteria:

  * Diplegic cerebral palsy patients
  * Both Girls and boys included
  * Age limit 6-12 years
  * CP child with Gross Motor Function Classification System (GMFCS) level III and IV(20)
  * CP child at MACS level II and III

Exclusion Criteria:

* • Patients with history of injury in 1 year.

  * Patients who cannot obey commands
  * CP children with associated scoliosis

Where it's running

  • Acme Medical center, Liaqat medical center
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.