Play-based nerve mobilization to improve hand strength and dexterity in children with diplegic cerebral palsy
Official title: Effects of Play Based Neural Mobilisation Activities on Hand Grip Strength and Dexterity in Cerebral Palsy Children
Run by Riphah International University · NCT07428928 · Data updated 2026-11-12
This trial will try adding play-based nerve mobilization to regular physical therapy to see if it improves hand grip strength and dexterity in children aged 6–12 with diplegic cerebral palsy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 12 Years |
| Sex | All |
| Enrollment | 34 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | October 29, 2025 |
| Main results expected | February 20, 2026 |
| Study ends | February 20, 2026 |
| Registry record updated | February 24, 2026 |
| Trial ID | NCT07428928 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 6–12 with diplegic cerebral palsy who are GMFCS level III–IV and MACS II–III, can follow commands, and have no major injuries in the past year.
✕Probably not a fit
Children who cannot follow commands, have a recent upper-limb injury, associated scoliosis, or non-diplegic forms of cerebral palsy are unlikely to benefit from this specific program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, single-blind controlled trial will enroll 16 children (age 6–12) with diplegic cerebral palsy (GMFCS III–IV, MACS II–III) at clinics in Lahore and randomly assign them to routine physical therapy with or without play-based neural mobilization. The intervention uses game-like activities (for example, a Simon Says format) to mobilize the ulnar, median, and radial nerves alongside standard therapy. Primary outcomes are hand grip strength measured with a dynamometer and manual dexterity measured with a pegboard test, collected over a 10-month study period. Convenience sampling is used and data will be analyzed in SPSS.
Why it matters
Potential benefit: If successful, this low-cost, play-based addition could improve hand strength and dexterity and help children with daily self-care and play.
How similar studies have gone: Neural mobilization has shown functional and pain benefits in some musculoskeletal and neuropathic adult studies, but play-based nerve mobilization specifically in children with cerebral palsy is novel and evidence is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria: * Diplegic cerebral palsy patients * Both Girls and boys included * Age limit 6-12 years * CP child with Gross Motor Function Classification System (GMFCS) level III and IV(20) * CP child at MACS level II and III Exclusion Criteria: * • Patients with history of injury in 1 year. * Patients who cannot obey commands * CP children with associated scoliosis
Where it's running
-
Acme Medical center, Liaqat medical center
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Uzma Irshad, MS-PT — Riphah International University
- Study coordinator: IMRAN AMJAD, PhD
- Email: imran.amjad@riphah.edu.pk
- Phone: 9233224390125
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy
This study tests whether Sensory Integration Therapy helps improve gross motor function more than standard physical therapy in children aged 4–10 with mixed cerebral palsy.
-
Turkish version of ABILHAND-Kids Young CP: translation, adaptation, and reliability
A Turkish version of the ABILHAND-Kids Young CP questionnaire is being created and tested to see if it reliably measures manual ability in 2-to-7-year-olds with cerebral palsy, based on parent reports.
-
Multisite upper limb surgery in children with unilateral cerebral palsy
This study looks at whether individualized multisite upper limb surgery helps improve hand function in kids with hemiplegic cerebral palsy, using each child as their own control before and after surgery.
-
Spinal Stimulation During Walking to See If Spasticity Lessens in Cerebral Palsy
This study tests whether walking with non-invasive spinal stimulation reduces leg muscle tightness and improves walking in children and young adults with cerebral palsy.
-
Combined leg nerve blocks for kids with cerebral palsy after surgery
This study tests whether adding two nerve blocks to standard anesthesia helps control pain in children with cerebral palsy after lower limb surgery.
-
Smartphone gait checks for kids with unilateral spastic CP
This study tests whether a phone’s accelerometer can reliably measure walking in children with unilateral spastic cerebral palsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.