Clinical trial Recruiting at 1 site Observational Ages 18 and up

Platinum chemotherapy and hearing in cancer patients from deprived communities

Official title: Chemotherapy-Induced Hearing Loss and Health Inequality

Run by Lancaster University · NCT07553481 · Data updated 2026-11-12

This study tests how platinum-based chemotherapy affects hearing in cancer patients living in the North West of England and whether socioeconomic deprivation influences risk.

More Chemotherapy trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment172 (estimated)
SponsorLancaster University
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Lancaster, Lancashire)
StatusRecruiting
StartedMay 2, 2026
Main results expectedSeptember 1, 2028
Study endsSeptember 1, 2028
Registry record updatedSeptember 10, 2026
Trial IDNCT07553481 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults in North West England receiving platinum-based chemotherapy, able to complete online tests, and fluent in English.

Probably not a fit

Patients who are not treated with platinum-based chemotherapy or who do not meet the online testing requirements may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines hearing changes in cancer patients treated with platinum-based chemotherapy, focusing on how deprivation status may relate to risk. It will collect hearing and cognitive test results, along with demographic and health information, to understand patterns of hearing loss. The goal is to inform future care by identifying whether disadvantaged groups experience greater burden and whether screening or support needs differ by socioeconomic status.

Why it matters

Potential benefit: If successful, findings could guide targeted screening and supportive care to reduce communication difficulties for patients at higher risk of hearing loss.

How similar studies have gone: Previous work has documented ototoxicity from platinum agents, but this project adds a health inequity dimension that is less explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients receiving platinum-based chemotherapy drugs
* Living and treated within North West England
* Able to complete an online hearing and cognitive test
* Fluent in English

Exclusion Criteria:

* Following cancer types: brain tumour/metastasis, head + neck, skin cancers around the ear, and adenoid cystic carcinoma of the auditory cortex
* World Health Organisation performance status score of 3 or more
* Stage 4 cancer
* History of childhood deafness
* Current or recent ear infections
* Cochlear implant user
* Known neurological impairment (e.g., stroke, traumatic brain injury, dementia)
* Patients who look capacity to consent or complete study tasks

Where it's running

  • Lancaster University
    Lancaster, Lancashire, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.