Pilot return-to-work brain health program for stroke survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial delivers the Train-Your-Brain Stroke Recovery Programme in community settings, led by registered clinical neuropsychologists, to stroke survivors with mild cognitive impairment who are aiming to return to work. It uses a mixed-methods design combining feasibility and acceptability measures with pre- and post-intervention cognitive tests, vocational outcomes, and exploratory neuroplasticity biomarkers. Caregivers are included to support skill generalization and to capture psychosocial and functional effects. Key outcomes include cognitive performance, return-to-work status, fatigue, self-care, and measures of brain mechanism change.

Why it matters

Who can join: the full rules

Inclusion Criteria (for stroke survivors):

* Between 21 to 65 years old
* Ability to provide informed consent
* Consent to recording / photo-taking
* Living in the community with at least three months after stroke
* Looking to return to work or switch jobs after stroke
* No significant aphasia or physical disability issues which will impede them from performing cognitive tasks in the interventions and assessments
* No major psychiatric illnesses
* Able to understand and converse in English
* Score on MoCA ≤22 and/or SDMT ≤13 (for those educated ≤6 years) or SDMT ≤32 (for those educated \>6 years)
* Meet criteria for Mild Cognitive Impairment based on the Vascular Dementia Battery

Inclusion Criteria (for caregivers):

* At least 21 years old
* Ability to provide informed consent
* Consent to recording / photo-taking
* Staying with or having knowledge of the stroke survivor's functioning
* No major psychiatric illnesses
* Able to understand and converse in English

Exclusion Criteria (for stroke survivors):

* Less than 21 years old
* More than 65 years old
* Unable to provide informed consent
* Refuse recording
* Not living in the community and having less than three months after stroke
* Significant aphasia or physical disability issues which will impede them from performing cognitive tasks in the interventions and assessments
* Major psychiatric illnesses
* Not able to understand and converse in English

Exclusion Criteria (for caregivers):

* Less than 21 years old
* Unable to provide informed consent
* Refuse recording
* Not staying with or not having knowledge of the stroke survivor's functioning
* Major psychiatric illnesses
* Not able to understand and converse in English

Where it's running

• National University of Singapore
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Yanhong Dong
• Email: nurdy@nus.edu.sg
• Phone: 65-65168686

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Deep phenotyping to explore recovery in young adults after stroke

  This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.

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• Stem cell therapy for chronic stroke recovery

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  Recruiting Phase 2 Hokkaido University Hospital · Sapporo, Hokkaido · NCT06752720

• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

  This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

  This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07921108

• Remote Ischaemic Conditioning for Fatigue After Stroke 2

  Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.

  Recruiting Phase 2 Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT07914647

• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.