Clinical trial Recruiting at 1 site Interventional Ages 20 to 55

Pilates or diaphragmatic breathing added to moderate treadmill exercise for people with pre-hypertension.

Official title: Additional Effects of Pilates Breathing and Diaphragmatic Breathing Combined With Moderate Intensity Continuous Treadmill Training on Blood Pressure, Chest Expansion, Pulmonary Function and Quality Of Life in Pre-hypertensive Patients

Run by Foundation University Islamabad · NCT07529821 · Data updated 2026-11-12

This trial will test whether adding Pilates breathing or diaphragmatic breathing to moderate treadmill workouts helps adults with pre-hypertension lower blood pressure, improve lung function, chest expansion, and quality of life.

More Pre Hypertension trials

Quick facts

Study typeInterventional
Ages20 Years to 55 Years
SexAll
Enrollment45 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad)
StatusRecruiting
StartedFebruary 28, 2026
Main results expectedMay 15, 2026
Study endsMay 15, 2026
Registry record updatedApril 14, 2026
Trial IDNCT07529821 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are sedentary adults aged 20–55 with systolic BP 120–139 mmHg or diastolic BP 80–89 mmHg who can safely perform moderate exercise and agree to attend supervised sessions.

Probably not a fit

People with established hypertension (≥140/90 mmHg), significant cardiopulmonary disease, musculoskeletal or neurological conditions that prevent exercise, pregnancy, or those already in structured exercise programs are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a three-arm randomized controlled trial enrolling 45 sedentary adults aged 20–55 with pre-hypertension, randomized to treadmill plus Pilates breathing, treadmill plus diaphragmatic breathing, or treadmill alone. Interventions are delivered three times per week for six weeks, with treadmill sessions performed at 55–70% of maximum heart rate and breathing exercises for 10–15 minutes per session. Primary and secondary outcomes including blood pressure, pulmonary function, chest expansion, and quality of life are measured before and after the intervention. Data will be analyzed using standard statistical methods (SPSS) to compare changes between groups.

Why it matters

Potential benefit: If successful, adding brief breathing exercises to moderate treadmill training could help delay progression to hypertension and improve respiratory function and quality of life in people with pre-hypertension.

How similar studies have gone: Previous research shows aerobic exercise and slow deep-breathing techniques can lower blood pressure, but combining treadmill MICT with Pilates-specific breathing is relatively novel and less well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Prehypertensive individuals (SBP 120-139 mmHg or DBP 80-89 mmHg)
* Age 20-55 years
* Both male and female
* Sedentary individuals according to IPAQ
* Willing to participate and provide informed consent

Exclusion Criteria:

* Diagnosed hypertension (≥140/90 mmHg)
* Cardiopulmonary diseases (COPD, asthma, CAD, heart failure)
* Musculoskeletal conditions preventing exercise
* Neurological disorders
* Pregnancy
* Participation in structured exercise in last 3 months

Where it's running

  • Foundation University Islamabad
    Islamabad, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.