Clinical trial Recruiting at 1 site Interventional Ages 70 and up

Physical exercise and cognitive training to improve quality of life in older adults

Official title: Health-related Quality of Life in Elderly Adults Following Physical Exercise and Cognitive Training: a Randomized-controlled Trial

Run by University Hospital of Ferrara · NCT07244536 · Data updated 2026-11-12

This project will test whether physical exercise, cognitive training, or both can improve quality of life, thinking, and mobility in people aged 70 and older.

More Elderly (People Aged 65 or More) trials

Quick facts

Study typeInterventional
Ages70 Years and up
SexAll
Enrollment156 (estimated)
SponsorUniversity Hospital of Ferrara
Academic / other
Locations1 site (Ferrara)
StatusRecruiting
StartedNovember 15, 2025
Main results expectedOctober 31, 2027
Study endsOctober 31, 2028
Registry record updatedDecember 12, 2025
Trial IDNCT07244536 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are people aged 70 or older who can give informed consent, are able to partake in physical exercise, and do not have severe cognitive impairment or major visual loss.

Probably not a fit

Patients with absolute contraindications to exercise, severe cognitive impairment (MoCA ≤ 12), severe visual impairment, or who cannot attend in-person sessions are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial enrolls adults aged 70 and older and assigns them to one of three intervention groups combining physical exercise and/or cognitive training. Interventions are delivered in person at a single center and are intended to target quality of life, cognitive performance, and mobility. Outcome measures will include standardized quality-of-life questionnaires, cognitive tests such as the MoCA, and mobility assessments over the intervention period. Participants with absolute contraindications to exercise, severe cognitive impairment, or severe visual loss are excluded.

Why it matters

Potential benefit: If effective, the interventions could help older adults preserve or improve quality of life, thinking skills, and physical mobility.

How similar studies have gone: Previous trials have shown modest benefits of physical exercise and cognitive training on mobility and cognition in older adults, though results for combined interventions have been mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male and female
* Age ≥ 70 years
* Provision of the informed consent form

Exclusion Criteria:

* Absolute contraindications to physical exercise (e.g. NYHA class IV heart failure, unstable angina, etc.)
* Pregnancy
* Severe cognitive impairment, defined as a MoCa score ≤ 12
* Severe visual impairment or blindness

Where it's running

  • Esercizio Vita
    Ferrara, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.