Physical exercise and cognitive training to improve quality of life in older adults
Health-related Quality of Life in Elderly Adults Following Physical Exercise and Cognitive Training: a Randomized-controlled Trial
This project will test whether physical exercise, cognitive training, or both can improve quality of life, thinking, and mobility in people aged 70 and older.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 156 (estimated) |
| Ages | 70 Years and up |
| Sex | All |
| Sponsor | University Hospital of Ferrara Academic / other |
| Locations | 1 site (Ferrara) |
| Trial ID | NCT07244536 on ClinicalTrials.gov |
What this trial studies
The trial enrolls adults aged 70 and older and assigns them to one of three intervention groups combining physical exercise and/or cognitive training. Interventions are delivered in person at a single center and are intended to target quality of life, cognitive performance, and mobility. Outcome measures will include standardized quality-of-life questionnaires, cognitive tests such as the MoCA, and mobility assessments over the intervention period. Participants with absolute contraindications to exercise, severe cognitive impairment, or severe visual loss are excluded.
Who should consider this trial
Good fit: Ideal participants are people aged 70 or older who can give informed consent, are able to partake in physical exercise, and do not have severe cognitive impairment or major visual loss.
Not a fit: Patients with absolute contraindications to exercise, severe cognitive impairment (MoCA ≤ 12), severe visual impairment, or who cannot attend in-person sessions are unlikely to benefit from this program.
Why it matters
Potential benefit: If effective, the interventions could help older adults preserve or improve quality of life, thinking skills, and physical mobility.
How similar studies have performed: Previous trials have shown modest benefits of physical exercise and cognitive training on mobility and cognition in older adults, though results for combined interventions have been mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female * Age ≥ 70 years * Provision of the informed consent form Exclusion Criteria: * Absolute contraindications to physical exercise (e.g. NYHA class IV heart failure, unstable angina, etc.) * Pregnancy * Severe cognitive impairment, defined as a MoCa score ≤ 12 * Severe visual impairment or blindness
Where this trial is running
Ferrara
- Esercizio Vita — Ferrara, Italy (Recruiting)
Study contacts
- Study coordinator: Luca Pomidori Principal Investigator, PhD
- Email: luca.pomidori@gmail.com
- Phone: 00393455984607
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.