Physical activity program to reduce sitting and increase activity after upper aerodigestive tract cancer treatment
Effect of Physical Activity Program on Sedentary and Physical Activity Level of Patients With Upper Aerodigestive Tract Cancer
NA · Centre Hospitalier de Valence · NCT06184880
This study will test whether an 18-month physical activity program can reduce sedentary time and increase physical activity for adults treated for localized upper aerodigestive tract (head and neck) cancer.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 96 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier de Valence (other) |
| Locations | 1 site (Valence) |
| Trial ID | NCT06184880 on ClinicalTrials.gov |
What this trial studies
APAORL2 is a randomized, open-label, controlled single-center trial enrolling 96 adults treated for localized upper aerodigestive tract cancer. Participants are randomized 1:1 to either standard care with physical activity recommendations or standard care plus a structured physical activity program delivered during treatment and the post-treatment phase, with remote sessions available via internet-connected devices. The primary outcome compares sedentary behavior and physical activity levels after the treatment phase, and secondary outcomes include quality of life and fatigue measured over an 18-month follow-up. The intervention is behavioral, aiming for sustained changes in daily activity patterns rather than introducing new medical treatments.
Who should consider this trial
Good fit: Ideal candidates are adults with newly diagnosed, histologically confirmed, non-metastatic upper aerodigestive tract cancer, a life expectancy of at least 18 months, and access to a smartphone, tablet, or computer for remote sessions.
Not a fit: Patients with contraindications to moderate physical activity or those who cannot be followed or participate remotely for the duration of the 18-month program are unlikely to benefit.
Why it matters
Potential benefit: If successful, the program could reduce sitting time, increase daily physical activity, and improve quality of life and fatigue for people treated for head and neck cancer.
How similar studies have performed: Physical activity interventions have shown benefits in other cancer populations, but evidence is more limited specifically for upper aerodigestive tract (head and neck) cancer and for long-term behavioral programs.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥18 years * newly diagnosed, histologically proven Upper Aerodigestive Tract Cancer, non-metastatic, * life expectancy ≥18 months * having a smartphone, tablet or computer with an internet connection enabling remote physical Activity sessions for the experimental group Exclusion Criteria: * Presenting a contraindication to moderate physical activity * Deprived of their liberty by court or administrative decision * Unable to be followed for medical, social, family, geographic or psychological reasons for the duration of the study,
Where this trial is running
Valence
- Ch Valence — Valence, France (RECRUITING)
Study contacts
- Principal investigator: Guillaume Guillaume — CH VALENCE
- Study coordinator: Guillaume Buiret
- Email: gbuiret@ch-valence.fr
- Phone: +33475752555
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Upper Aerodigestive Tract Cancer, Head and Neck Cancer, Physical Activity, head and neck cancer