Photon-counting CT for lung imaging in people with COPD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project will recruit participants from the Duke COPDGene Phase 4 cohort who consent to undergo an additional photon-counting CT (PCCT) scan at Duke University Hospital. Scans will be acquired with a PCCT-specific protocol and also compared to conventional energy-integrating CT where available. Investigators will reconstruct the PCCT images using multiple post-acquisition parameter settings and apply recently developed harmonization techniques. Quantitative metrics such as Perc15, LAA-950, HU accuracy, Pi10, and airway wall percentage will be compared across reconstructions to identify reproducible acquisition and processing protocols.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* This study recruit from the Duke-COPDGene Phase 4 study. All participants from this cohort is eligible and they will be included if they consent.

Exclusion Criteria:

* This study recruit from the Duke-COPDGene Phase 4 study. All participants from this cohort is eligible and they will be included if they consent.

Where it's running

• Duke University Hospital
  Durham, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Ehsan Abadi, Ph.D. — Duke University
• Study coordinator: Wendy Curry
• Email: wendy.curry@duke.edu
• Phone: 919-668-8281

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.