Pharmacogenomic decision-making during elective surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study involves adults scheduled for elective surgical procedures at the University of Chicago, where blood samples will be collected for preemptive genotyping. The genotyping will identify actionable germline variants that predict drug response or toxicity risk. Results will be provided to healthcare providers through a secure web portal, enabling personalized drug-gene clinical decision support. The initial phase will include approximately 100 patients over a six-month period to evaluate the integration of pharmacogenomic data into clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients who have planned elective surgical procedures at the University of Chicago
* Must be aged 18 years or older

Exclusion Criteria:

* Patients who have undergone, or are being actively considered for, liver or kidney transplantation
* Patients with known active or prior leukemia.
* Inability to understand and give informed consent to participate.

Where it's running

• University Of Chicago Medicine Comprehensive Cancer Center
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: Peter O'Donnell — University of Chicago
• Study coordinator: Cancer Clinical Trials Office
• Email: cancerclinicaltrials@bsd.uchicago.edu
• Phone: 1-855-702-8222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.