Pharmacist-led intervention to improve blood pressure control in hypertensive patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cluster randomized controlled trial aims to evaluate the effectiveness of a pharmacist-led multifaceted intervention on poorly controlled hypertensive patients across eight tertiary hospitals in China. The study will enroll 800 participants, randomly assigning hospitals to either an intervention or control group. The intervention includes health education, home blood pressure telemonitoring, medication consultation, reminders, and individualized medication regimens, while the control group receives standard health education. Outcomes will be assessed at multiple time points to measure changes in blood pressure control, adherence to medication, and cardiovascular disease risk.

Why it matters

Who can join: the full rules

Inclusion Criteria (subjects must meet all of the following criteria to be included):

* 1\) age 18-80 years;
* 2\) patients with hypertension (diagnostic criteria: defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg according to the "Guidelines for the prevention and treatment of hypertension in China in 2023", based on the blood pressure measurement of three times on different days), who are currently taking anti-hypertensive medication and are judged by the research physician to have poor blood pressure control;
* 3\) able to use smartphones and WeChat proficiently, and can communicate and upload pictures proficiently;
* 4\) able to take care of yourself and communicate normally, and willing to cooperate with the research physician to complete the study and follow-up;
* 5\) permanent residents of the city where the center is located;
* 6\) voluntarily participate and sign the informed consent form

Exclusion Criteria(subjects will be excluded if they meet any of the following criteria):

* 1\) patients with advanced disease (such as patients undergoing dialysis or liver failure), or with a life expectancy of less than 2 years as determined by the research physician;
* 2\) combined with psychiatric disease, cognitive impairment, communication disorder, or inability to cooperate with the researchers;
* 3\) combined with cerebrovascular disease, stroke, severe liver and kidney dysfunction, severe heart failure, cancer and history of organ transplantation, etc.;
* 4\) patients who are pregnant, breastfeeding, or planning to conceive in the next 2 years.

Where it's running

• Xijing hospital
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Study coordinator: Qianqian Dong, Doctor
• Email: dongqq@fmmu.edu.cn
• Phone: +8613720451039

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using low-dose aspirin after preeclampsia to improve recovery

  This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.

  Recruiting Phase 4 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06281665

• IMB-guided health education to boost medication taking and blood pressure control in adults with hypertension

  This study tests a health-literacy program based on Information-Motivation-Behavioral Skills to help adults with hypertension who don’t take their medicines regularly to take them more consistently and better control their blood pressure.

  Recruiting at 8 sites Bahir Dar University · Ādēt and 7 other locations · NCT07894068

• Renal Nerve Stimulation to Help Blood Pressure in AF and HFpEF

  This study tests whether stimulating the kidneys with a catheter can safely lower blood pressure in adults with atrial fibrillation and HFpEF who also have hypertension.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07893821

• Hypertension: Does Education Help Patients Manage Blood Pressure Better?

  This study tests whether structured patient education improves blood pressure control and self-management in adults with hypertension who speak Turkish.

  Recruiting Inonu University · Batman, Center · NCT07890090

• High BMI and periodontitis in Thai adults under 60

  This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.

  Recruiting Mahidol University · Bangkok, Ratchathewi · NCT07880717

• Long-term GW906 treatment for people with essential hypertension

  This trial tests whether long-term GW906 injections are safe and effective for adults with essential hypertension who completed an earlier GW906 study.

  Recruiting Shenzhen Salubris Pharmaceuticals Co., Ltd. · Shanghai, Shanghai Municipality · NCT07879755

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.