Clinical trial Recruiting at 1 site Interventional Ages 40 to 70

Personalized treatment for urogenital cancers based on microbiome analysis

Official title: Personalized Treatment of Urogenital Cancers Depends on the Microbiome

Run by Zealand University Hospital · NCT03962920 · Data updated 2026-11-12

This study tests if giving antibiotics based on a person's microbiome can help improve recovery and treatment outcomes for people with localized urogenital cancers compared to those who get a placebo.

Quick facts

Study typeInterventional
Ages40 Years to 70 Years
SexAll
Enrollment28 (estimated)
SponsorZealand University Hospital
Academic / other
Locations1 site (Roskilde)
StatusRecruiting
StartedMay 1, 2020
Main results expectedMay 1, 2025
Study endsMay 1, 2027
Registry record updatedJanuary 30, 2024
Trial IDNCT03962920 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with a biopsy-verified diagnosis of localized urological cancer.

Probably not a fit

Patients with a history of genitourinary tract cancers, recent hospitalization, or those with diabetes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of microbiome on the treatment of urogenital cancers by comparing two groups of patients undergoing surgical treatment. One group will receive antibiotics while the other will receive a placebo, allowing researchers to assess the role of microbiome in recovery and treatment outcomes. The study aims to determine if personalized treatment based on microbiome can improve patient outcomes in localized urological cancers.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and personalized treatment strategies for patients with urogenital cancers.

How similar studies have gone: While the role of microbiome in cancer treatment is an emerging field, this specific approach has not been widely tested, making it a novel investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Biopsy verified diagnosis of urological cancer, localized disease

Exclusion Criteria:

* Hospitalization within three months of surgery
* Antibiotics within three months of surgery
* Infectious disease, including UTI's within three months of surgery
* History of cancers of the genitourinary tract
* Diabetes

Where it's running

  • Zealand University Hospital
    Roskilde, Denmark
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.