Personalized treatment for urogenital cancers based on microbiome analysis
Personalized Treatment of Urogenital Cancers Depends on the Microbiome
NA · Zealand University Hospital · NCT03962920
This study tests if giving antibiotics based on a person's microbiome can help improve recovery and treatment outcomes for people with localized urogenital cancers compared to those who get a placebo.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 28 (estimated) |
| Ages | 40 Years to 70 Years |
| Sex | All |
| Sponsor | Zealand University Hospital (other) |
| Locations | 1 site (Roskilde) |
| Trial ID | NCT03962920 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of microbiome on the treatment of urogenital cancers by comparing two groups of patients undergoing surgical treatment. One group will receive antibiotics while the other will receive a placebo, allowing researchers to assess the role of microbiome in recovery and treatment outcomes. The study aims to determine if personalized treatment based on microbiome can improve patient outcomes in localized urological cancers.
Who should consider this trial
Good fit: Ideal candidates are patients with a biopsy-verified diagnosis of localized urological cancer.
Not a fit: Patients with a history of genitourinary tract cancers, recent hospitalization, or those with diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective and personalized treatment strategies for patients with urogenital cancers.
How similar studies have performed: While the role of microbiome in cancer treatment is an emerging field, this specific approach has not been widely tested, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Biopsy verified diagnosis of urological cancer, localized disease Exclusion Criteria: * Hospitalization within three months of surgery * Antibiotics within three months of surgery * Infectious disease, including UTI's within three months of surgery * History of cancers of the genitourinary tract * Diabetes
Where this trial is running
Roskilde
- Zealand University Hospital — Roskilde, Denmark (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Microbial Disease