Personalized treatment for lung cancer patients with pleural effusion using organoids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on lung cancer patients suffering from pleural effusion by utilizing patient-derived tumor organoids to predict drug sensitivity. The research involves acquiring clinical samples, culturing organoids in vitro, and conducting drug sensitivity tests to guide treatment decisions. By correlating the sensitivity results with clinical medication guidance, the study aims to enhance treatment plans tailored to individual patient needs. The study is conducted at a single center, Henan Cancer Hospital, with a sample capacity of 20 patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

(1)18 years of age and above; (2) Understand and voluntarily sign the informed consent form (ICF), and have good compliance, and can cooperate with diagnosis and follow-up; (3)ECOG score 0-2; (4) Accompanied by malignant pleural effusion; Presence of at least one measurable lesion as assessed by the investigator;

Exclusion Criteria:

1. A history of malignant tumor in the past 5 years;
2. Complicated with serious complications, such as uncontrolled heart disease, severe arrhythmia requiring medical treatment, persistent watery diarrhea, etc.;
3. Pregnant or lactating female patients; Patients deemed unsuitable for participation in this study.

Where it's running

• Henan cancer hospital
  Zhengzhou, Henan, China Recruiting

Study contacts

• Study coordinator: Qiming Wang
• Email: qimingwang1006@126.com
• Phone: 13783590691

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.