Personalized treatment for children with disruptive behavior and their parents
Matching Assessment and Treatment for Children With Disruptive Behaviour and Their Parents
This study is testing a personalized treatment approach for children aged 6-12 with disruptive behavior and their parents to see if it can improve the effectiveness of therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 6 Years to 12 Years |
| Sex | All |
| Sponsor | Centre for Addiction and Mental Health Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT06373484 on ClinicalTrials.gov |
What this trial studies
This study aims to develop and test personalized profiles for children aged 6-12 with Disruptive Behaviour Disorder (DBD) and their parents, based on psychological, emotional, and neuropsychological indicators. By collecting measures before and after cognitive behavioral therapy (CBT), the researchers will use statistical modeling to identify which sub-groups of children and parents are most likely to benefit from CBT and Behavioral Parent Training (BPT). The goal is to enhance treatment effectiveness by tailoring approaches to individual needs.
Who should consider this trial
Good fit: Ideal candidates include children aged 6-12 with clinically significant disruptive behavior and their willing parents.
Not a fit: Patients with pervasive developmental disorders, autism, or significant cognitive delays may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve treatment outcomes for children with disruptive behavior and their families.
How similar studies have performed: Other studies have shown promise in using personalized approaches for behavioral disorders, indicating potential for success in this novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Child is borderline/clinically at risk on the Child Behaviour Checklist (CBCL) or Teacher Report Form (TRF) (T-score greater than or equal to 60 on Externalizing Problems composite scale or a T-score greater than or equal to 65 on the Oppositional Defiant Disorder and/or Conduct Disorder scales) * Child has clinically severe impairment in the interpersonal relations (greater than 3), functioning in schoolwork (greater than 3), or total domains (greater than 15) on the Columbia Impairment scale. * Parent is able and willing to participate in a group treatment Exclusion Criteria: * Child has an ongoing query or diagnosis of Pervasive Developmental Disorder or Autism or Asperger's Disorder * Evidence of cognitive delays or an intellectual disability (based on the Kauffman Brief Intelligence Test-2 (KBIT-2), verbal and/or IQ composite standard score below 80 or collateral information) * Child behaviour or emotional functioning that make group participation not possible * Child preference for individual treatment. * Parent behaviour or emotional functioning that make group participation not possible * Parent preference for individual treatment.
Where this trial is running
Toronto, Ontario
- Centre for Addiction and Mental Health — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Brendan F. Andrade, PhD — Centre for Addiction and Mental Health
- Study coordinator: Brendan F. Andrade, PhD
- Email: brendan.andrade@camh.ca
- Phone: 416-535-8501
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.