Personalized treatment for children with disruptive behavior and their parents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop and test personalized profiles for children aged 6-12 with Disruptive Behaviour Disorder (DBD) and their parents, based on psychological, emotional, and neuropsychological indicators. By collecting measures before and after cognitive behavioral therapy (CBT), the researchers will use statistical modeling to identify which sub-groups of children and parents are most likely to benefit from CBT and Behavioral Parent Training (BPT). The goal is to enhance treatment effectiveness by tailoring approaches to individual needs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Child is borderline/clinically at risk on the Child Behaviour Checklist (CBCL) or Teacher Report Form (TRF) (T-score greater than or equal to 60 on Externalizing Problems composite scale or a T-score greater than or equal to 65 on the Oppositional Defiant Disorder and/or Conduct Disorder scales)
* Child has clinically severe impairment in the interpersonal relations (greater than 3), functioning in schoolwork (greater than 3), or total domains (greater than 15) on the Columbia Impairment scale.
* Parent is able and willing to participate in a group treatment

Exclusion Criteria:

* Child has an ongoing query or diagnosis of Pervasive Developmental Disorder or Autism or Asperger's Disorder
* Evidence of cognitive delays or an intellectual disability (based on the Kauffman Brief Intelligence Test-2 (KBIT-2), verbal and/or IQ composite standard score below 80 or collateral information)
* Child behaviour or emotional functioning that make group participation not possible
* Child preference for individual treatment.
* Parent behaviour or emotional functioning that make group participation not possible
* Parent preference for individual treatment.

Where it's running

• Centre for Addiction and Mental Health
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Brendan F. Andrade, PhD — Centre for Addiction and Mental Health
• Study coordinator: Brendan F. Andrade, PhD
• Email: brendan.andrade@camh.ca
• Phone: 416-535-8501

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Augmenting Parent Management Training with a Smartphone Tool

  This study tests whether adding a smartphone app to parent management training helps reduce irritability and temper outbursts in kids aged 8–13 with disruptive behavior disorders.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07764536

• Therapy approaches for irritability in youths: active treatments vs nonactive psychoeducation

  This study tests whether active psychotherapies for irritability in kids aged 8–16.5 years work better than nonactive, time-matched psychoeducation for children and their parents.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07640802

• Preventive interventions for at-risk high school students with conduct problems

  This study is testing three different programs to see if they can help high school students who are at risk for behavior problems feel better and make better choices.

  Recruiting Phase 1/2 University of Minnesota · Minneapolis, Minnesota · NCT06831123

• Understanding children's emotions in therapy

  This study is testing a new therapy approach for kids aged 8 to 15 with anxiety, depression, trauma, or behavior issues to see if it helps them feel better compared to those who aren't receiving treatment right away.

  Recruiting at 2 sites University of Guelph · Guelph, Ontario and 1 other locations · NCT05637320

• Understanding brain development and behaviors like impulsivity and compulsivity

  This study looks at how brain development affects impulsive and compulsive behaviors in people aged 6 to 80 to see if there are links between genetics and brain features.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04631042

• Foquest in older adults with ADHD: daily methylphenidate for 65+

  This study tests whether once-daily Foquest helps symptoms in adults 65 and older with ADHD.

  Recruiting Phase 4 Dar Clinical Research Inc. · Ottawa, Ontario · NCT07710014

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.