Personalized single-session intervention for mild-to-moderate depression and anxiety
Randomized Controlled Trial for Personalized Need-focused Single-Session Interventions
This study is testing if a personalized one-time therapy session can help people with mild-to-moderate anxiety and depression feel better compared to a standard therapy session.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 240 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Bar-Ilan University, Israel Academic / other |
| Locations | 2 sites (Berkeley, California and 1 other locations) |
| Trial ID | NCT05953779 on ClinicalTrials.gov |
What this trial studies
This clinical trial is a two-site randomized controlled trial aimed at evaluating the effectiveness of single-session interventions for individuals experiencing mild-to-moderate anxiety and depression. Participants will receive either a personalized intervention tailored to their specific psychosocial needs or a standard intervention. Each session lasts 90 minutes and includes psychoeducational components, with follow-up check-ins to assess progress. The study seeks to determine if personalized approaches yield greater symptom relief compared to standard methods.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with mild-to-moderate symptoms of depression or anxiety, as indicated by a score of 5 or above on the Hamilton Rating Scale for Depression.
Not a fit: Patients with severe mental health conditions, such as severe depression, severe anxiety disorders, or psychotic disorders, will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could provide a rapid and effective treatment option for individuals struggling with mild-to-moderate anxiety and depression.
How similar studies have performed: Other studies have shown promise in using personalized interventions for mental health, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criterion. \* a score of 5 or above on the Hamilton Rating Scale for Depression (HRSD). Exclusion Criteria based on Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders (DIAMOND). * Psychotic Disorders (hallucinations or delusions) * Past or current mania, current hypo-mania. * Anorexia Disorder * Current Obsessive-Compulsive and related Disorders rated as moderate and above. * Alcohol or drug abuse rated as moderate and above. * Panic Disorder rated as moderate and above. * Agoraphobia rated as moderate and above. * Premenstrual dysphoric disorder rated as moderate and above. * Current Post-Traumatic Stress Disorder rated as moderate and above. * binge eating rated as moderate and above. * Phobia rated as severe and above. * Somatic symptom disorder rated as severe and above. * Illness Anxiety Disorder rated as severe and above. * MDD rated as severe and above. * GAD rated as severe and above. * Social Anxiety rated as severe and above. * Separation anxiety rated as severe and above.
Where this trial is running
Berkeley, California and 1 other locations
- University of California, Berkeley — Berkeley, California, United States (Recruiting)
- Bar-Ilan University — Ramat Gan, Israel (Recruiting)
Study contacts
- Study coordinator: Eshkol Rafaeli, PhD
- Email: eshkol.rafaeli@gmail.com
- Phone: +972-3-7384660
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.