Personalized rhythmic music therapy to improve walking and reduce freezing in Parkinson's disease
Official title: Rhythmic Auditory Stimulaton Using Personalized Music Therapy in Parkinson's Disease
Run by University of Lahore · NCT07378722 · Data updated 2026-11-12
This program will try personalized rhythmic music plus physical therapy to improve walking speed, balance, and reduce freezing in people with Parkinson's disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 55 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Lahore Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | February 5, 2026 |
| Main results expected | April 5, 2026 |
| Study ends | April 6, 2026 |
| Registry record updated | January 30, 2026 |
| Trial ID | NCT07378722 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people aged 45–55 with clinically diagnosed Parkinson's disease (Queen Square Brain Bank criteria), MMSE >23, and mild balance impairment (BBS 21–40) who can attend in-person sessions.
✕Probably not a fit
Patients with severe cognitive impairment, advanced or unstable medical conditions, significant hearing or musculoskeletal problems, other neurologic disorders affecting gait, recent neurologic music therapy, or those outside the 45–55 age range may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will enroll 42 people with Parkinson's disease and randomly assign them to receive personalized rhythmic auditory stimulation (RAS) combined with conventional physical therapy or conventional physical therapy alone. Treatments are delivered three times per week for eight weeks, and primary outcomes include freezing of gait, gait velocity, and balance performance measured with standard clinical scales. Participants are recruited from Lahore hospitals and must meet Queen Square Brain Bank diagnostic criteria with specified cognitive and balance scores. Computer-generated randomization and blinded outcome measures are used to compare group changes over the treatment period.
Why it matters
Potential benefit: If successful, the intervention could improve gait speed and stability, reduce freezing episodes, lower fall risk, and help participants maintain greater independence.
How similar studies have gone: Previous studies of rhythmic auditory stimulation and music-based cues have shown improvements in gait timing, stride length, and freezing in Parkinson's disease, although personalized-music RAS has been less extensively studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * According to the Queen Square Brain Bank standard , clinical diagnosed patients of PD Both male and females ages 45-55 The mini mental state examination scale MMSE screening without severe cognitive impairment,can cooperate with this study \> 23 Mild bergs balance scale BBS score (21-40 ) score Exclusion Criteria: * A history of neoplasms; severe cardiovascular, respiratory, visual, auditory, andmuscular-skeletal disease; other neurological conditions; and neurologic music therapy inthelast3 months. Other disorders that could potentially influence balance and walking.
Where it's running
-
Shadman Medical Center
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Rumesa Aslam, MSPTN — The University of Lahore, Lahore
- Study coordinator: Rumesa Butt, MSPTN
- Email: rumesaaslam5@gmail.com
- Phone: 03044020918
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Ginger as a Modifier of Ghrelin Levels in Parkinson’s Disease and REM Sleep Behavior Disorder
This study tests whether ginger capsules can raise ghrelin levels in people with Parkinson’s disease, REM sleep behavior disorder, and healthy controls.
-
Intraoperative Microelectrode Recordings with MAVEN vs Standard Equipment
This study tests whether MAVEN can match the recording data collected during DBS surgery for movement disorders using standard equipment.
-
Mental imagery with self-regulation to help daily activities in Parkinson's disease
This study tests whether a six-week program of mental imagery combined with self-regulation can help people with Parkinson’s perform daily activities better than standard learning or exercise.
-
Real-world experiences of Inbrija for Parkinson's OFF episodes
This study looks at how people with Parkinson’s who use Inbrija for OFF episodes feel and function in daily life.
-
Gut methane and Parkinson's: measuring if a probiotic helps people with Parkinson's, REM sleep behavior disorder, or cognitive concerns
This study tests whether a probiotic containing Limosilactobacillus reuteri can help people with Parkinson's disease, those at high risk for PD, and related cognitive issues by potentially improving gut methane levels and overall symptoms.
-
Test of RO7568282 in early Parkinson's disease
This study tests whether RO7568282, compared with placebo, is safe and helps people with early Parkinson's disease who are already taking levodopa.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.