Personalized rhythmic music therapy to improve walking and reduce freezing in Parkinson's disease
Rhythmic Auditory Stimulaton Using Personalized Music Therapy in Parkinson's Disease
This program will try personalized rhythmic music plus physical therapy to improve walking speed, balance, and reduce freezing in people with Parkinson's disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 45 Years to 55 Years |
| Sex | All |
| Sponsor | University of Lahore Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT07378722 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial will enroll 42 people with Parkinson's disease and randomly assign them to receive personalized rhythmic auditory stimulation (RAS) combined with conventional physical therapy or conventional physical therapy alone. Treatments are delivered three times per week for eight weeks, and primary outcomes include freezing of gait, gait velocity, and balance performance measured with standard clinical scales. Participants are recruited from Lahore hospitals and must meet Queen Square Brain Bank diagnostic criteria with specified cognitive and balance scores. Computer-generated randomization and blinded outcome measures are used to compare group changes over the treatment period.
Who should consider this trial
Good fit: Ideal candidates are people aged 45–55 with clinically diagnosed Parkinson's disease (Queen Square Brain Bank criteria), MMSE >23, and mild balance impairment (BBS 21–40) who can attend in-person sessions.
Not a fit: Patients with severe cognitive impairment, advanced or unstable medical conditions, significant hearing or musculoskeletal problems, other neurologic disorders affecting gait, recent neurologic music therapy, or those outside the 45–55 age range may not benefit from this intervention.
Why it matters
Potential benefit: If successful, the intervention could improve gait speed and stability, reduce freezing episodes, lower fall risk, and help participants maintain greater independence.
How similar studies have performed: Previous studies of rhythmic auditory stimulation and music-based cues have shown improvements in gait timing, stride length, and freezing in Parkinson's disease, although personalized-music RAS has been less extensively studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * According to the Queen Square Brain Bank standard , clinical diagnosed patients of PD Both male and females ages 45-55 The mini mental state examination scale MMSE screening without severe cognitive impairment,can cooperate with this study \> 23 Mild bergs balance scale BBS score (21-40 ) score Exclusion Criteria: * A history of neoplasms; severe cardiovascular, respiratory, visual, auditory, andmuscular-skeletal disease; other neurological conditions; and neurologic music therapy inthelast3 months. Other disorders that could potentially influence balance and walking.
Where this trial is running
Lahore, Punjab Province
- Shadman Medical Center — Lahore, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Rumesa Aslam, MSPTN — The University of Lahore, Lahore
- Study coordinator: Rumesa Butt, MSPTN
- Email: rumesaaslam5@gmail.com
- Phone: 03044020918
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.