Personalized placental risk assessment to customize pregnancy care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study enrolls pregnant participants before 22 weeks' gestation and follows them through delivery and the neonatal period up to 28 days. Participants will undergo scheduled ultrasounds and blood draws during pregnancy, and clinical delivery and newborn data will be collected. The combined imaging, laboratory, and clinical data will be used to develop and validate a predictive model of placental insufficiency. The aim is to identify pregnancies at higher risk for placental dysfunction so care can be tailored earlier.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant
* Age 15 or older
* No known major fetal anatomic or genetic abnormalities
* Singleton gestation
* Planning to deliver at Oregon Health \& Science University
* Prior to 22 weeks' gestation

Exclusion Criteria:

* Decisional impairment
* Multiple gestation
* Known fetal growth restriction or major congenital anomaly
* Inability to consent
* Inability to attend study visits

Where it's running

• Oregon Health & Science University
  Portland, Oregon, United States Recruiting

Study contacts

• Principal investigator: Karen Gibbins — Oregon Health and Science University
• Study coordinator: Women's Health Research Unit Department of Ob/Gyn
• Email: whru@ohsu.edu
• Phone: 503-494-3666

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Ophthalmic Artery Doppler to predict labor problems before induction

  This study tests whether measuring the ophthalmic artery Doppler in pregnant people at term who are being induced can help predict intrapartum fetal distress.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome, rm · NCT07846137

• Womb Watch: using a smartphone app to detect fetal movements

  This study tests a smartphone app to help pregnant people track fetal movements and see if it can better detect movement changes that might signal risk.

  Recruiting at 3 sites University of Texas at Austin · Austin, Texas and 2 other locations · NCT07626112

• Pravastatin for severe early-onset placental insufficiency

  This trial will test whether pravastatin can safely prolong pregnancy and lower risks for pregnant people with severe early-onset preeclampsia or early-onset IUGR between 24+0 and 29+6 weeks.

  Recruiting Phase 2 Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Barcelona, Barcelona and 1 other locations · NCT07098975

• Walk With Me for Perinatal Grief

  A mobile app-based program (Along With Me) with or without a Peer Guide is tested to see if it lowers posttraumatic stress and suicidal thoughts in bereaved parents after pregnancy or early infant loss.

  Recruiting Oregon Research Behavioral Intervention Strategies, Inc. · Eugene, Oregon and 1 other locations · NCT07011940

• Examining how assisted reproductive technologies affect pregnancy outcomes

  This study is trying to see if different assisted reproductive technologies affect the health of pregnancies and if they are linked to risks like growth problems or stillbirth.

  Recruiting Aristotle University Of Thessaloniki · Pleven and 5 other locations · NCT06918236

• Evaluating new ultrasound techniques for assessing placental health

  This study is testing new ultrasound techniques to see if they can help tell the difference between healthy pregnancies and those with fetal growth issues.

  Recruiting Carilion Clinic · Roanoke, Virginia · NCT06861309

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.