Personalized physical activity thresholds for COPD patients

Developing Personalised, Relative Intensity Physical Activity Thresholds for Accelerometer-Derived Measures of Physical Activity in COPD (IMPACT)

This study is trying to understand how people with COPD feel about their physical activity levels and see if personalized exercise plans can help them stay active after rehabilitation.

Quick facts

• Study type: Observational
• Enrollment: 70 (estimated)
• Ages: 40 Years and up
• Sex: All
• Sponsor: University of Leicester (other)
• Locations: 1 site (Leicester, Leicestershire)
• Trial ID: NCT06330623 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore how individuals with Chronic Obstructive Pulmonary Disease (COPD) perceive physical activity intensity and to evaluate the differences between absolute and relative physical activity levels. In Phase 1, participants will engage in semi-structured interviews to discuss their experiences with COPD and physical activity, while Phase 2 will involve physical activity testing before and after pulmonary rehabilitation using activity monitors. The goal is to provide a user-friendly evaluation of physical activity that can enhance personalized exercise prescriptions for COPD patients.

Who should consider this trial

Good fit: Ideal candidates are adults aged 40 and older with a confirmed diagnosis of COPD who can communicate in English.

Not a fit: Patients with severe psychiatric disorders or those unable to participate in pulmonary rehabilitation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more tailored exercise recommendations that improve physical activity levels and overall health for COPD patients.

How similar studies have performed: While the approach of evaluating physical activity in COPD is not widely tested, similar studies have shown promise in enhancing rehabilitation outcomes through personalized exercise prescriptions.

Eligibility criteria

Phase 1:

Inclusion Criteria:

* Willing and able to provide informed consent for participation in the research.
* The patient has a confirmed diagnosis of COPD using spirometry (based on GOLD criteria (Agustí et al., 2023).
* Male or female, aged 40+ years
* Able to communicate in written and spoken English.

Exclusion Criteria:

* Unable to provide valid informed consent.
* Severe psychiatric disorders
* Aged less than 40 years
* Unable to understand written or spoken English.

Phase 2:

Inclusion Criteria:

* Willing and able to provide informed consent for participation in the research.
* The patient has a confirmed diagnosis of COPD using spirometry (based on GOLD criteria.
* The patient is referred for PR at the UHL.
* Male or female, aged 40+ years
* Able to communicate in written and spoken English

Exclusion Criteria:

* Unable to provide valid informed consent.
* Lack of motivation to participate in PR programme.
* Any-contra-indications absolute or relative to exercise training.
* Has had a cardiac event within last 6 weeks
* Severe psychiatric disorders
* Patients with a history of MRSA +ve screens (patients can be assessed and given an exercise programme but cannot attend the classes. Patients need to have 3 consecutive -ve MRSA swabs before they can attend).
* Aged less than 40 years
* Unable to understand written or spoken English.

Where this trial is running

Leicester, Leicestershire

• NIHR Leicester Biomedical Research Centre - Respiratory — Leicester, Leicestershire, United Kingdom (RECRUITING)

Study contacts

• Principal investigator: University of Leicester University of Leicester — University of Leicester
• Study coordinator: Phoebe H Lloyd-Evans

Conditions: Chronic Obstructive Pulmonary Disease, Absolute Intensity, Activity Monitors, Exercise Capacity, Physical Activity, Relative Intensity