Personalized music-enhanced aerobic training for inpatients recovering from subacute stroke
Official title: Evaluation of the Effectiveness of a Personalized Music-Based Aerobic Exercise Rehabilitation Program for Patients With Subacute Stroke
Run by University of Medicine and Pharmacy at Ho Chi Minh City · NCT07503522 · Data updated 2026-11-12
This program will test whether adding personalized rhythmic music to gentle, supervised aerobic exercise helps inpatients in the subacute phase of stroke improve movement, balance, and mood.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 92 (estimated) |
| Sponsor | University of Medicine and Pharmacy at Ho Chi Minh City Academic / other |
| Locations | 1 site (Ho Chi Minh City, Ho Chi Minh) |
| Status | Recruiting |
| Started | April 1, 2026 |
| Main results expected | January 2028 |
| Study ends | May 2028 |
| Registry record updated | April 13, 2026 |
| Trial ID | NCT07503522 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) with a clinically and radiologically confirmed subacute stroke who can sit unsupported, follow simple assessment questions, have MMSE ≥ 10, and can consent or have a legal representative provide consent.
✕Probably not a fit
Patients with significant cardiac contraindications, musculoskeletal conditions that prevent safe exercise, severe cognitive impairment (MMSE ≤ 9), or severe aphasia that prevents participation are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants will receive the hospital's standard physical therapy and the intervention group will also join 30-minute music-based aerobic sessions five days per week for six weeks, with exercises adapted to each patient's functional level. Sessions use rhythmic music to guide arm, leg, and trunk movements while heart rate is monitored and rehabilitation therapists provide direct supervision for safety. Outcomes are measured before and after the 6-week program using standardized tests of motor function, balance, depressive symptoms, and independence in daily activities. The protocol is designed for inpatient delivery without specialized equipment to increase accessibility for patients with weakness or limited mobility.
Why it matters
Potential benefit: If successful, this approach could improve mobility, balance, and mood during the critical subacute recovery period and make inpatient rehab more engaging.
How similar studies have gone: Previous research supports benefits of aerobic exercise and rhythmic auditory stimulation for movement and mood after stroke, but fully personalized, low-intensity music-aerobic programs delivered to subacute inpatients are less extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * Clinically and radiologically confirmed diagnosis of subacute stroke. * Able to understand and respond to assessment questions. * No significant visual or hearing impairment. * Mini-Mental State Examination (MMSE) ≥ 10. * Able to sit unsupported. * Provided informed consent (patient or legal representative). Exclusion Criteria: * Recent myocardial infarction or congestive heart failure. * Severe cardiac arrhythmia or resting systolic blood pressure \> 200 mmHg. * Hypertrophic cardiomyopathy or severe aortic stenosis. * Musculoskeletal disorders contraindicating exercise. * Psychiatric disorders interfering with participation. * Severe aphasia preventing assessment. * Moderate-to-severe dementia (MMSE ≤ 9).
Where it's running
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Ho Chi Minh City Orthopedics and Rehabilitation Hospital (Hospital 1A)
Ho Chi Minh City, Ho Chi Minh, Vietnam Recruiting
Study contacts
- Principal investigator: Minh Tu Trinh, MD — Ho Chi Minh City Orthopedics and Rehabilitation Hospital (Hospital 1A)
- Study coordinator: Minh Tu Trinh, MD
- Email: tmtu.ncs25@ump.edu.vn
- Phone: +84947969399
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.