Personalized music-enhanced aerobic training for inpatients recovering from subacute stroke
Evaluation of the Effectiveness of a Personalized Music-Based Aerobic Exercise Rehabilitation Program for Patients With Subacute Stroke
This program will test whether adding personalized rhythmic music to gentle, supervised aerobic exercise helps inpatients in the subacute phase of stroke improve movement, balance, and mood.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 92 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Medicine and Pharmacy at Ho Chi Minh City Academic / other |
| Locations | 1 site (Ho Chi Minh City, Ho Chi Minh) |
| Trial ID | NCT07503522 on ClinicalTrials.gov |
What this trial studies
Participants will receive the hospital's standard physical therapy and the intervention group will also join 30-minute music-based aerobic sessions five days per week for six weeks, with exercises adapted to each patient's functional level. Sessions use rhythmic music to guide arm, leg, and trunk movements while heart rate is monitored and rehabilitation therapists provide direct supervision for safety. Outcomes are measured before and after the 6-week program using standardized tests of motor function, balance, depressive symptoms, and independence in daily activities. The protocol is designed for inpatient delivery without specialized equipment to increase accessibility for patients with weakness or limited mobility.
Who should consider this trial
Good fit: Adults (≥18) with a clinically and radiologically confirmed subacute stroke who can sit unsupported, follow simple assessment questions, have MMSE ≥ 10, and can consent or have a legal representative provide consent.
Not a fit: Patients with significant cardiac contraindications, musculoskeletal conditions that prevent safe exercise, severe cognitive impairment (MMSE ≤ 9), or severe aphasia that prevents participation are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, this approach could improve mobility, balance, and mood during the critical subacute recovery period and make inpatient rehab more engaging.
How similar studies have performed: Previous research supports benefits of aerobic exercise and rhythmic auditory stimulation for movement and mood after stroke, but fully personalized, low-intensity music-aerobic programs delivered to subacute inpatients are less extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * Clinically and radiologically confirmed diagnosis of subacute stroke. * Able to understand and respond to assessment questions. * No significant visual or hearing impairment. * Mini-Mental State Examination (MMSE) ≥ 10. * Able to sit unsupported. * Provided informed consent (patient or legal representative). Exclusion Criteria: * Recent myocardial infarction or congestive heart failure. * Severe cardiac arrhythmia or resting systolic blood pressure \> 200 mmHg. * Hypertrophic cardiomyopathy or severe aortic stenosis. * Musculoskeletal disorders contraindicating exercise. * Psychiatric disorders interfering with participation. * Severe aphasia preventing assessment. * Moderate-to-severe dementia (MMSE ≤ 9).
Where this trial is running
Ho Chi Minh City, Ho Chi Minh
- Ho Chi Minh City Orthopedics and Rehabilitation Hospital (Hospital 1A) — Ho Chi Minh City, Ho Chi Minh, Vietnam (Recruiting)
Study contacts
- Principal investigator: Minh Tu Trinh, MD — Ho Chi Minh City Orthopedics and Rehabilitation Hospital (Hospital 1A)
- Study coordinator: Minh Tu Trinh, MD
- Email: tmtu.ncs25@ump.edu.vn
- Phone: +84947969399
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.