Personalized Mediterranean Diet for Children
Personalizing Mediterranean Diet in Children: the Ferrero Pilot Trial.
This study is testing how healthy kids react to Mediterranean and regular diets to see if personalized meal plans can help them manage their blood sugar and prevent obesity later in life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 6 Years to 11 Years |
| Sex | All |
| Sponsor | Weizmann Institute of Science Academic / other |
| Locations | 1 site (Reẖovot) |
| Trial ID | NCT03627923 on ClinicalTrials.gov |
What this trial studies
This study investigates how healthy children respond to Mediterranean and regular diets, focusing on their glucose levels. By measuring various factors such as blood tests, lifestyle, and gut microbiome, researchers aim to develop machine-learning algorithms that predict individual glucose responses to food. The goal is to create personalized dietary recommendations that could help reduce obesity and related diseases in children and later in adulthood. This approach is novel as personalized nutrition has not been extensively studied in pediatric populations.
Who should consider this trial
Good fit: Ideal candidates are healthy children aged 6 to 11 years who are at Tanner stage 1.
Not a fit: Patients with chronic illnesses, recent acute diseases, or those on specific medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to tailored dietary plans that improve children's metabolic health and reduce obesity-related risks.
How similar studies have performed: While personalized nutrition has shown promise in adults, this approach in children is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy children * 6-11 years of age * Tanner 1 • Exclusion criteria: * Acute disease 2 months prior to enrollment * Chronic illness in the past 5 years, including inflammatory, metabolic, neoplastic, congenital and infectious disease. * Use of medications (e.g. Antibiotics/antifungal, PPI, analgesics) and any antibiotics 3 months prior to the first visit, PPI one month prior to the beginning of the study or use of medication during the study. * Treatment with anti-diabetic medications; * Neuro-psychiatric disorders * Cancer and recent anticancer treatment * Eating disorders (Anorexia nervosa. Bulimia nervosa. Binge eating disorder, Night eating syndrome). * Inability of the participant and/or nuclear family to follow and utilize the smartphone application. * Dietary restrictions or specific dietary regimen
Where this trial is running
Reẖovot
- Weizmann Institute of Science — Reẖovot, Israel (Recruiting)
Study contacts
- Principal investigator: Eran Elinav, Prof — Weizmann Institute of Science
- Study coordinator: Aurelie Bukimer Mimran
- Email: aurelie.bukimer@weizmann.ac.il
- Phone: +97289529089
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.