Personalized home activity program for people with mild-to-moderate dementia after hospital discharge

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will compare patients receiving routine post-discharge care to those given a dyadic personalized home-based activity program. In the hospital, clinicians tailor an individualized activity plan and train the primary family caregiver while providing activity resources and support. After discharge, the trained caregiver delivers the intervention at home with ongoing professional support and follow-up. The main outcome is change in behavioral and psychological symptoms of dementia measured using standard instruments such as the Neuropsychiatric Inventory.

Why it matters

Who can join: the full rules

Inclusion Criteria Patients

* Be aged ≥ 60 years;
* Have a diagnosis of dementia according to ICD-10 criteria, with a Clinical Dementia Rating (CDR) score of 1-2 (mild-to-moderate stage);
* Retain basic verbal communication ability;
* Present at least one neuropsychiatric symptom (a score ≥ 1 on any single item) within the past month, as evaluated by the Neuropsychiatric Inventory (NPI);
* Be medically fit for hospital discharge and scheduled to receive home care post-discharge;
* Be willing to participate in this study and provide written informed consent.

Family Caregivers

* Be aged ≥ 18 years;
* Have kinship with the patient (e.g., spouse, children, siblings, etc.);
* Undertake primary care responsibilities on an unpaid, non-professional basis, and have the longest average daily care hours among all family caregivers;
* Be willing to assume continuous home care responsibilities for at least 3 months post-discharge;
* Have intact verbal communication skills;
* Possess basic proficiency in operating the WeChat application (a widely used social communication application in China), including independently sending and receiving messages, as well as making voice and video calls；
* Be willing to participate in this study and provide written informed consent.

Exclusion Criteria Patients

* Have severe somatic diseases (e.g., malignant tumors, heart failure, physical disabilities) or severe psychiatric disorders;
* Have severe visual or hearing impairment;
* Have dementia secondary to the following conditions: central nervous system diseases (e.g., encephalitis, brain tumors, epilepsy, multiple sclerosis, Parkinson's disease), nutritional and metabolic disorders (e.g., thyroid dysfunction, vitamin B12 or folate deficiency), substance or alcohol dependence, and other potential causes of secondary dementia;
* Suffer from severe physical or mental disorders, extreme debilitation, long-term bedridden status, end-stage disease with a life expectancy of less than six months, or be unable to cooperate with or tolerate the study intervention;
* Be enrolled in any other clinical research that may interfere with the outcomes of this study.

Family Caregivers

* Have severe somatic diseases (e.g., malignant tumors, heart failure, physical disabilities) or severe psychiatric disorders;
* Have severe visual or hearing impairment;
* Be enrolled in any other clinical research that may interfere with the outcomes of this study.

Where it's running

• Union Hospital Affiliated to Fujian Medical University
  Fujian, Fuzhou, China Recruiting

Study contacts

• Study coordinator: Xiaozhen Fu
• Email: 15160301901@163.com
• Phone: 15160301901

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.