Personalized exercise programs to lower dementia risk in older Veterans with Motoric Cognitive Risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls community-dwelling Veterans age 65 and older with Motoric Cognitive Risk (slow gait plus cognitive complaints) who receive VA primary care. Participants are randomized using a sequential multiple assignment randomized trial (SMART) design to receive functional power training, music-based digital walking therapy, or a combination, with treatment pathways adapted based on response. The study measures mobility and cognitive outcomes to identify which personalized exercise strategies work best for different patients. Successful completion will provide preliminary evidence to guide tailored rehabilitation approaches for older Veterans at risk for dementia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 65
2. Receiving VA primary care
3. Community-dwelling
4. Motoric Cognitive Risky Syndrome i. Slow gait speed ii. Subjective cognitive concerns/complaints

Exclusion Criteria:

1. Non-English speaking
2. Presence of a terminal disease
3. Major medical problem
4. Myocardial infarction or major surgery in the previous 3 months
5. 3-point walking pattern
6. Dementia diagnostic
7. Mobility disability

Where it's running

• VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Elisa Ogawa, PhD MS BS — VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
• Study coordinator: Elisa Ogawa, PhD MS BS
• Email: elisa.ogawa@va.gov
• Phone: (857) 364-4011

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Figure-of-8 Walking Test in Motoric Cognitive Risk Syndrome

  This observational study tests whether the Figure-of-8 Walk Test is a reliable and valid way to measure dynamic balance and gait in people with Motoric Cognitive Risk Syndrome.

  Recruiting Balikesir University · Balıkesir, Bigadiç · NCT07586553

• How doing a thinking task while walking affects balance and gait in Motoric Cognitive Risk Syndrome

  This test will see if doing a thinking task while walking changes walking speed and balance in people aged 65 and older with Motoric Cognitive Risk Syndrome.

  Recruiting Balikesir University · Balıkesir, Bigadiç · NCT07572968

• Laser-based visual mapping test for Motoric Cognitive Risk Syndrome

  This project tests whether a laser-based visual feedback task can reliably measure visuospatial processing, reaction time, and arm control in people aged 65 and older with Motoric Cognitive Risk Syndrome.

  Recruiting Balikesir University · Balıkesir, Bigadiç · NCT07572942

• Motor-cognitive training with a virtual reality treadmill for older adults at risk of dementia

  This study tests whether combining motor and cognitive training on a virtual reality treadmill can help older adults with motoric cognitive risk syndrome improve walking speed and thinking skills more than traditional treadmill training.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT07223905

• Exergaming versus neuromuscular exercise for older adults with Motoric Cognitive Risk

  This trial will test whether a video-game-based exercise program (exergaming) or a traditional neuromuscular exercise program better improves walking and thinking in people aged 65 and older with Motoric Cognitive Risk Syndrome.

  Recruiting Istanbul University - Cerrahpasa · Balıkesir · NCT07045259

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.