Personalized exercise program for older adults with knee osteoarthritis and heart issues
Algarve Active Ageing - Cardiac and Osteoarthritis Rehabilitation: Personalized Physical Exercise Protocol in After Acute Myocardial Infarction or Cardiovascular Risk and Knee Osteoarthritis, a Randomized Controlled Trial
This study is testing a personalized exercise program for older adults with knee osteoarthritis and heart issues to see if it can improve their quality of life and reduce pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv Research network |
| Locations | 1 site (Faro, Algarve) |
| Trial ID | NCT05999110 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of a personalized exercise program designed for individuals aged 50 and older who are recovering from acute myocardial infarction or have cardiovascular risk while also suffering from knee osteoarthritis. Participants will be randomly assigned to either an exercise group, which will undergo a 12-week supervised exercise regimen, or a control group with no intervention. Both groups will receive behavioral and nutritional counseling to promote healthy lifestyle changes. The study will assess improvements in quality of life, functionality, and pain levels before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 or older with knee pain and a history of acute myocardial infarction or cardiovascular risk.
Not a fit: Patients who have had an acute myocardial infarction within the last 12 months or have significant cognitive impairment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance the quality of life and functional abilities of patients with knee osteoarthritis and cardiovascular issues.
How similar studies have performed: Previous studies have indicated a relationship between osteoarthritis and cardiovascular diseases, suggesting that this personalized exercise approach may be beneficial, although this specific intervention is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 50 or older; Knee pain, Morning stiffness that lasts no longer than 30 minutes and one of the following: crepitus, restricted function, bony enlargement. Acute Myocardial Infarction with myocardial lesion detected by abnormal cardiac biomarkers evidencing acute myocardial ischemia; High risk level in the Systematic Coronary Risk Evaluation (SCORE2) or the Systematic Coronary Risk Evaluation Older Person (SCORE2 O.P.) cardiovascular risk algorithm or prior cardiovascular disease; Independent gait Exclusion Criteria: * Occurrence of acute myocardial infarction with less than 12 months; Cognitive impairment- Montreal Cognitive Assessment (MoCA); Type 1 diabetes or insulin dependence; Pacemaker device; Knee prosthesis; Currently doing formal exercise session for more that 30 minutes per week; Class III or IV angina according to Canadian Cardiovascular Society criteria; Class III or IV symptoms according to New York Heart Association criteria; Type 2 Myocardial Infarction; Uncontrolled and symptomatic cardiac arrythmia with hemodynamic impact; Severe and symptomatic aortic valve stenosis; Uncontrolled and symptomatic heart failure; Active myocarditis, pericarditis or endocarditis; Acute aortic syndrome; Known or suspected desiccant aneurism; Acute systemic infection.
Where this trial is running
Faro, Algarve
- Ad-Abc — Faro, Algarve, Portugal (Recruiting)
Study contacts
- Principal investigator: Sandra R Pais, PhD — Ad-Abc
- Study coordinator: Marta S Botelho, PhD
- Email: marta.botelho@abcmedicalg.pt
- Phone: +351 916785430
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.