Personalized cognitive behavior therapy for chronic primary pain

Personalising Cognitive Behaviour Therapy for Chronic Primary Pain Using Network Analysis - A Single Case Experimental Design Study With Multiple Baselines

Not applicable Interventional University of Kaiserslautern-Landau · NCT06179784

This study is testing a personalized approach to cognitive behavior therapy for people with chronic pain to see if it can help them feel better by using data from their daily experiences.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment12 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Kaiserslautern-Landau Academic / other
Locations1 site (Landau In Der Pfalz)
Trial IDNCT06179784 on ClinicalTrials.gov

What this trial studies

This study aims to personalize cognitive behavior therapy (CBT) for patients with chronic primary pain (CPP) using network analysis. Participants will complete ecological momentary assessments via a mobile app to gather data on their symptoms and experiences over 21 days. This data will inform an algorithmic decision tool that selects individualized treatment targets and interventions. The study will evaluate the feasibility and acceptance of this personalized approach among patients and therapists, as well as its effectiveness in improving patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults with a primary diagnosis of chronic pain lasting at least six months and who have access to a compatible smartphone.

Not a fit: Patients with acute suicidality, substance abuse, psychosis, or those focusing solely on migraine or headache may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and tailored treatments for individuals suffering from chronic primary pain.

How similar studies have performed: While personalized approaches to therapy are gaining traction, this specific use of network analysis in CBT for chronic primary pain is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* main diagnosis of chronic pain (i.e. pain persists for at least 6 months and is the most prominent/most burdensome symptom)
* subjective impairment/disability (yes-no)
* access to a smartphone compatible with the app mPath

Exclusion Criteria:

* acute hazard due to suicidality, substance abuse, and/or psychosis
* only migraine/headache or migraine/headache are the focus of pain
* analphabetism
* insufficient German knowledge
* current psychotherapy
* current participation in another intervention study
* physical inability to take part in therapy and study sessions

Where this trial is running

Landau In Der Pfalz

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Primary PainChronic PainSingle Case Experimental DesignEcological Momentary AssessmentNetwork analysisCognitive Behaviour Therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.