Clinical trial Recruiting at 1 site Observational Ages 12 and up

Personalized cancer treatment based on tumor molecular profiling

Official title: Individualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project

Run by National Cancer Centre, Singapore · NCT02806388 · Data updated 2026-11-12

This study is testing whether analyzing the genetic makeup of a person's tumor can help doctors choose the best cancer treatment for them.

Quick facts

Study typeObservational
Ages12 Years and up
SexAll
Enrollment5500 (estimated)
SponsorNational Cancer Centre, Singapore
Academic / other
Locations1 site (Singapore)
StatusRecruiting
StartedOctober 2011
Main results expectedDecember 31, 2026
Study endsDecember 31, 2027
Registry record updatedMay 13, 2026
Trial IDNCT02806388 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with a confirmed diagnosis of solid tumors who are suitable for systemic treatment and clinical trials.

Probably not a fit

Patients who do not have a solid tumor or those who are not eligible for systemic treatment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on screening the molecular profile of tumors to enhance the selection of anticancer treatments, particularly for allocation to available clinical trials. It involves collecting archival or freshly obtained tumor tissue, as well as blood, pleural fluid, fine needle aspirates, and saliva to analyze the genetic makeup of the tumor. The goal is to provide personalized therapy tailored to the individual molecular profile of the patient’s tumor.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and targeted cancer treatments for patients.

How similar studies have gone: Other studies utilizing molecular profiling for personalized cancer treatment have shown promising results, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Confirmed histological diagnosis of solid tumor
* Suitable for systematic treatment and clinical trials
* ECOG (Eastern cooperative oncology group) performance status \< 2
* Able to provide tumor tissue for molecular profiling
* Able to understand and sign the informed consent form

Exclusion Criteria:

* None

Where it's running

  • National Cancer Centre, Singapore
    Singapore, Singapore
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.