Personalized approach to shoulder joint replacement

Multicenter Randomised Study of Personalized Instrument in Total Shoulder Arthroplasty The P.I.T.S.A. Study

NA · Université de Montréal · NCT03839758

This study is testing if using a personalized guide based on CT scans during shoulder replacement surgery can help people with shoulder arthritis recover better than using standard guides.

Quick facts

PhaseNA
Study typeInterventional
Enrollment112 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorUniversité de Montréal (other)
Locations1 site (Montreal, Quebec)
Trial IDNCT03839758 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a personalized glenoid guide in total shoulder arthroplasty for patients with shoulder arthritis. Participants will be randomized into two groups: one using a patient-specific guide based on preoperative CT scans and the other using a standard method with generic guides. The study aims to improve the precision of glenoid component implantation, which is crucial for reducing complications such as loosening and instability. Preoperative assessments will include demographic data, range of motion, quality of life, and functional status.

Who should consider this trial

Good fit: Ideal candidates are patients with shoulder osteoarthritis or avascular necrosis scheduled for elective primary total shoulder arthroplasty.

Not a fit: Patients with previous shoulder arthroplasty, inflammatory arthritis, or those who cannot commit to a two-year follow-up may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and reduced complications for patients undergoing shoulder replacement surgery.

How similar studies have performed: While the use of personalized guides in orthopedic surgery is gaining traction, this specific approach in total shoulder arthroplasty is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with shoulder osteaoarthritis and AVN

Exclusion Criteria:

* Patients with previous shoulder arthroplasty
* Patients with inflammatory arthritis and tumor
* Patients with previous shoulder surgery with metal implant
* Patients refusing 2-year follow-up
* Patients that does not speak English or French
* Patients with current or previous shoulder infection
* Patients with graft during surgery

Where this trial is running

Montreal, Quebec

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Shoulder Arthritis, Prothesis, Glenoid implantation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.